HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Phosphoribosylaminoimidazolecarboxamide Formyltransferase

An enzyme that catalyzes the conversion of aminoimidazole-4-carboxamide ribonucleotide to 5-formyl-aminoimidazole-4-carboxamide ribonucleotide in the purine de novo synthesis pathway. It requires the cofactor N(10)-FORMYLTETRAHYDROFOLATE as the formyl donor.
Also Known As:
AICAR Formyltransferase; AICAR Transformylase; AICARTFase; Aminoimidazolecarboxamide Ribonucleotide Transformylase; Formyltransferase, AICAR; Formyltransferase, Phosphoribosylaminoimidazolecarboxamide; Ribonucleotide Transformylase, Aminoimidazolecarboxamide; Transformylase, AICAR; Transformylase, Aminoimidazolecarboxamide Ribonucleotide; 5-amino-4-imidazolecarboxamide ribotide transformylase
Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Spurr, Ian B: 1 article (07/2012)
2. Birts, Charles N: 1 article (07/2012)
3. Benkovic, Stephen J: 1 article (07/2012)
4. Cuda, Francesco: 1 article (07/2012)
5. Blaydes, Jeremy P: 1 article (07/2012)
6. Tavassoli, Ali: 1 article (07/2012)
7. Tamura, Tsunenobu: 1 article (03/2010)
8. Baggott, Joseph E: 1 article (03/2010)
9. Micheli, Vanna: 1 article (02/2010)
10. Tozzi, Maria Grazia: 1 article (02/2010)

Related Diseases

1. Breast Neoplasms (Breast Cancer)
2. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
3. Neurologic Manifestations (Neurological Manifestations)
4. Neoplasms (Cancer)
5. Metabolic Diseases (Metabolic Disease)

Related Drugs and Biologics

1. Methotrexate (Mexate)
2. Phosphoribosylaminoimidazolecarboxamide Formyltransferase
3. purine
4. IMP cyclohydrolase
5. dihydrofolate
6. Phosphoribosylglycinamide Formyltransferase
7. 3-Deazauridine (3 Deazauridine)
8. Oxidoreductases
9. Nucleotides
10. Inosine Monophosphate (IMP)