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Phosphoribosylglycinamide Formyltransferase

An enzyme that catalyzes the transfer of a formyl group from N10-formyltetrahydrofolate to N1-(5-phospho-D-ribosyl)glycinamide to yield N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and tetrahydrofolate. It plays a role in the de novo purine biosynthetic pathway.
Also Known As:
2-Amino-N-Ribosylacetamide 5'-Phosphate Transformylase; 5'-Phosphoribosylglycinamide Transformylase; GAR Formyltransferase; GAR Transformylase; GARTFase; Glycinamide Ribonucleotide Transformylase; Glycinamideribotide Transformylase; 2 Amino N Ribosylacetamide 5' Phosphate Transformylase; 5' Phosphoribosylglycinamide Transformylase; 5'-Phosphate Transformylase, 2-Amino-N-Ribosylacetamide; Formyltransferase, GAR; Formyltransferase, Phosphoribosylglycinamide; Ribonucleotide Transformylase, Glycinamide; Transformylase, 2-Amino-N-Ribosylacetamide 5'-Phosphate; Transformylase, 5'-Phosphoribosylglycinamide; Transformylase, GAR; Transformylase, Glycinamide Ribonucleotide; Transformylase, Glycinamideribotide
Networked: 20 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Huang, Xiaodong: 1 article (07/2014)
2. Zhang, Yixin: 1 article (07/2014)
3. Cai, Jing: 1 article (07/2014)
4. Cui, Xiaopeng: 1 article (07/2014)
5. He, Song: 1 article (07/2014)
6. Ni, Runzhou: 1 article (07/2014)
7. Lu, Cuihua: 1 article (07/2014)
8. Yang, Dunpeng: 1 article (07/2014)
9. Lv, Liting: 1 article (07/2014)
10. Cong, Xia: 1 article (07/2014)

Related Diseases

1. Neoplasms (Cancer)
2. Leukemia
3. Lymphoma (Lymphomas)
4. Hepatocellular Carcinoma (Hepatoma)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. lometrexol
2. Folic Acid (Vitamin M)
3. Methotrexate (Mexate)
4. Thymidylate Synthase
5. purine
6. folylpolyglutamate synthetase
7. Phosphoribosylglycinamide Formyltransferase
8. Enzymes
9. 5,6,7,8-tetrahydrofolic acid (tetrahydrofolate)
10. Phosphoribosylaminoimidazolecarboxamide Formyltransferase

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)