Voltage-Dependent Anion Channels

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12 relevant articles (0 outcomes, 1 trials/studies) found for this Bio-Agent

Description: A family of voltage-gated eukaryotic porins that form aqueous channels. They play an essential role in mitochondrial CELL MEMBRANE PERMEABILITY, are often regulated by BCL-2 PROTO-ONCOGENE PROTEINS, and have been implicated in APOPTOSIS.

Also Known As:

Mitochondrial Pore Protein; Mitochondrial Porin; Pore Forming Protein VDAC; Porin, Mitochondria; Porins, Mitochondria; VDAC Mitochondrial Porin; VDAC Proteins; Voltage-Dependent, Anion-Selective Channel Forming Protein, Mitochondrial; Voltage-Dependent, Anion-Selective Channels; Anion Channels, Voltage-Dependent; Anion-Selective Channels Voltage-Dependent; Channels Voltage-Dependent, Anion-Selective; Mitochondria Porin; Mitochondria Porins; Mitochondrial Porin, VDAC; Pore Protein, Mitochondrial; Porin, Mitochondrial; Porin, VDAC Mitochondrial; Voltage Dependent Anion Channels; Voltage Dependent, Anion Selective Channels

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins

Proteins: 58433

Carrier Proteins: 7795

Membrane Transport Proteins: 93

Ion Channels: 2134

Porins: 61

Voltage-Dependent Anion Channels: 12

Voltage-Dependent Anion Channel 1: 7

Drosophila porin protein

Voltage-Dependent Anion Channel 2

Experts

1.	Simamura, Eriko: 1 article (06/2008)
2.	Shimada, Hiroki: 1 article (06/2008)
3.	Pedersen, Peter L: 1 article (06/2008)
4.	Hirai, Kei-Ichi: 1 article (06/2008)
5.	Hatta, Toshihisa: 1 article (06/2008)
6.	Carlen, P L: 1 article (01/2000)
7.	Huzar, D V: 1 article (01/2000)
8.	Perez Velazquez, J L: 1 article (01/2000)
9.	Frantseva, M V: 1 article (01/2000)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 03/11/1986 - "Hexokinase receptor complex in hepatoma mitochondria: evidence from N,N'-dicyclohexylcarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC." Order ALL the reference details at left...
2.	Neoplasms (Cancer) 06/01/2008 - "Voltage dependent anion channels (VDACs): a brief introduction with a focus on the outer mitochondrial compartment's roles together with hexokinase-2 in the "Warburg effect" in cancer." 06/01/2008 - "Recently, it was demonstrated that some anti-cancer agents used mitochondrial voltage-dependent anion channels (VDAC1-3 isoforms) as their pharmacological target. " 06/01/2008 - "Mitochondrial voltage-dependent anion channels (VDACs) as novel pharmacological targets for anti-cancer agents." 06/14/2007 - "Using affinity purification and mass spectrometry, we discovered that erastin acts through mitochondrial voltage-dependent anion channels (VDACs)--a novel target for anti-cancer drugs. " 08/01/2003 - "Potentially important up-regulated genes included gp96, lung resistance-related protein, galectin-3 binding protein, the M(r) 67,000 laminin receptor (on tumor vessels), and voltage-dependent anion channels. " Order ALL the reference details at left...
3.	Ischemia 01/01/2000 - "Mitochondrial porin required for ischemia-induced mitochondrial dysfunction and neuronal damage." 01/01/1999 - "Mitochondrial porin, a novel target to prevent ischemia-induced neurodegeneration?" 05/09/2008 - "Several phosphoproteins were detected, including voltage-dependent anion channels isoforms 1 and 2, but none showed significant IP-mediated changes either before ischemia or during ischemia and reperfusion, and neither Western blotting nor 2D fluorescence difference gel electrophoresis detected translocation of protein kinase C (alpha, epsilon, or delta isoforms), glycogen synthase kinase 3beta, or Akt to the mitochondria following IP. " Order ALL the reference details at left...
4.	Epidemic Louse-Borne Typhus (Typhus) 05/01/2009 - "We have recently shown that Rickettsia prowazekii (typhus group rickettsiae) cells incorporate human mitochondrial porin VDAC1. " Order ALL the reference details at left...
5.	African Trypanosomiasis (Nagana) 09/01/2009 - "Mitochondrial porin in Trypanosoma brucei, a unicellular parasitic protozoan and the causative agent of African trypanosomiasis, possesses a beta-barrel structure similar to the bacterial OM porin OmpA. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Hexokinase
2.	Dicyclohexylcarbodiimide (DCCD)
3.	Protein Kinase C-alpha
4.	Glycogen Synthase Kinases
5.	Galectin 3 (LGALS3)
6.	Protein Isoforms (Isoforms)
7.	Laminin Receptors
8.	Phosphoproteins
9.	Glycerol (Glycerine)
10.	Carrier Proteins (Binding Protein)

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