|1.||Kohno, Shigeru: 9 articles (01/2015 - 01/2003)|
|2.||Nagata, Kazuhiro: 8 articles (12/2014 - 01/2006)|
|3.||Koji, Takehiko: 5 articles (01/2015 - 01/2003)|
|4.||Sakamoto, Noriho: 4 articles (01/2014 - 04/2007)|
|5.||Kakugawa, Tomoyuki: 4 articles (01/2014 - 04/2007)|
|6.||Kubota, Hiroshi: 4 articles (01/2014 - 04/2007)|
|7.||Mukae, Hiroshi: 4 articles (01/2014 - 04/2007)|
|8.||Matsuoka, Yasuhiro: 4 articles (01/2014 - 01/2006)|
|9.||Abe, Katsushige: 4 articles (12/2012 - 01/2003)|
|10.||Miyazaki, Masanobu: 4 articles (12/2012 - 01/2003)|
08/01/2005 - "Heat shock protein 47 may play an important role in promoting the formation of pathological scar tissue."
11/01/2000 - "Heat shock protein 47 in renal scarring."
01/01/2005 - "To study the expression of heat shock protein 47 (HSP47) and its correlation to collagen deposition in pathological scar tissues. "
08/01/2005 - "To detect the expression of heat shock protein 47 mRNA in pathological scar tissue by using real-time fluorescent quantitative reverse transcription-polymerase chain reaction (RT-PCR). "
08/01/2005 - "[Detection of expression of heat shock protein 47 mRNA in pathological scar tissue by using real-time fluorescent quantitative RT-PCR]."
01/01/2014 - "In this study, we found that the expression of heat shock protein 47 was significantly increased in patients with Schistosoma-induced fibrosis, as well as in rodent models. "
01/01/2014 - "Involvement of heat shock protein 47 in Schistosoma japonicum-induced hepatic fibrosis in mice."
09/23/2011 - "Furthermore, regular exercise decreased the expression of heat shock protein 47, a marker of hepatic fibrosis, in the liver. "
03/01/2011 - "In this prospective study we assessed the expression of heat shock protein 47 (HSP47), a regulator of fibrosis, in the biopsies of nasal mucosa isolated from patients undergoing primary endoscopic DCR (EN-DCR). "
12/01/2009 - "The fibrosis markers heat shock protein 47, alpha-smooth muscle actin, and fibroblast specific protein-1 were overexpressed in ocular cGVHD epithelia. "
|3.||Idiopathic Pulmonary Fibrosis
09/01/2013 - "Serum heat shock protein 47 levels are elevated in acute exacerbation of idiopathic pulmonary fibrosis."
12/01/2000 - "In this study, we examined the expression of heat shock protein 47 and type I procollagen in 12 patients with usual interstitial pneumonia by immunohistochemistry on sequential sections. "
12/01/2000 - "Heat shock protein 47 was localized predominantly in alpha-smooth muscle actin-positive myofibroblasts and surfactant protein-A-positive type II pneumocytes in active fibrotic areas of usual interstitial pneumonia. "
12/01/2000 - "Our results suggest that myofibroblasts and type II pneumocytes play an important role in the progression of fibrosis through the induction of heat shock protein 47, which regulates the synthesis/assembly of type I procollagen in usual interstitial pneumonia. "
12/01/2000 - "The numbers of heat shock protein 47- and type I procollagen-positive cells to type II pneumocytes or myofibroblasts were significantly higher in usual interstitial pneumonia than in bronchiolitis obliterans organizing pneumonia and normal lung tissue specimens. "
|4.||Pulmonary Fibrosis (Hamman Rich Syndrome)
07/01/2004 - "The present study results showed that pirfenidone inhibited heat shock protein 47-positive cells and myofibroblasts, the principal cells responsible for the accumulation and deposition of extracellular matrix seen in pulmonary fibrosis."
06/14/2007 - "Introduction of antisense oligonucleotides to heat shock protein 47 prevents pulmonary fibrosis in lipopolysaccharide-induced pneumopathy of the rat."
04/24/2007 - "We reported previously that heat shock protein 47 (HSP47), a collagen-specific molecular chaperon, and collagen-1 synthesis were involved in pulmonary fibrosis, and that plasma levels of alpha-defensins (HNP; human neutrophil peptide), cationic proteins with antimicrobial and cytotoxic activity in neutrophils, were significantly higher in patients with idiopathic pulmonary fibrosis than in control subjects. "
05/01/2014 - "Heat shock protein 47 regulated by miR-29a to enhance glioma tumor growth and invasion."
01/01/2010 - "In previous studies we found expression of the protein colligin 2 (heat shock protein 47 (HSP47), SERPINH1) in glioma neovasculature while not in normal brain tissue. "
04/08/2014 - "To define heat shock protein 47 (HSP47) as a novel glioma-associated antigen and to preliminarily assess the association of cytotoxic T lymphocyte (CTL) responses to HSP47 with clinical outcomes in patients with glioblastomas (GBMs). "
|2.||Collagen Type I (Type I Collagen)
|7.||Proteins (Proteins, Gene)
|8.||Molecular Chaperones (Chaperone, Molecular)
|9.||Transforming Growth Factor beta (TGF-beta)
|1.||Angioplasty (Angioplasty, Transluminal)
|2.||Kampo Medicine (Kampo)
|4.||Photochemotherapy (Photodynamic Therapy)