HSC70 Heat-Shock Proteins

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18 relevant articles (0 outcomes, 2 trials/studies) found for this Bio-Agent

Description: A constitutively expressed subfamily of the HSP70 heat-shock proteins. They preferentially bind and release hydrophobic peptides by an ATP-dependent process and are involved in post-translational PROTEIN TRANSLOCATION.

Also Known As:

70 kDa Heat-Shock Cognate Protein; Clathrin Uncoating Protein; HSC73 Protein; 70 kDa Heat Shock Cognate Protein; HSC70 Heat Shock Proteins; Heat Shock Cognate 70 Protein; Heat-Shock Proteins, HSC70; Uncoating Protein, Clathrin; Heat-Shock Cognate 70 Protein; Hsc70 Protein

Bio-Agent Context: Research Results

Experts

1.	Margulis, B A: 1 article (07/2006)
2.	Andreeva, L I: 1 article (07/2006)
3.	Boĭkova, A A: 1 article (07/2006)

Related Diseases

1.	Glaucoma 05/01/2003 - "PURPOSE: To study the effects of geranylgeranylacetone (GGA) on the expression of inducible (HSP72) and constitutive (HSC70) heat shock proteins (HSPs) on retinal ganglion cells (RGCs) in a rat model of glaucoma. " 01/01/2003 - "PURPOSE: To study the effects of geranylgeranylacetone (GCA) on the expression of inducible (HSP72) and constitutive (HSC70) heat shock proteins (HSPs) on retinal ganglion cells (RGCs) in a rat model of glaucoma. " Order ALL the reference details at left...
2.	Shock 01/01/2008 - "Conversely, we demonstrate that incubation with the heat shock cognate 70 (Hsc70) protein prior to oxidative insult can protect MNs from oxidative stress. " 08/11/2000 - "DnaJ is an essential cochaperone of mammalian heat shock cognate 70 (hsc70) protein. " 04/01/1998 - "The modulation of the chaperone activity of the heat shock cognate Hsc70 protein in mammalian cells involves cooperation with chaperone cofactors, such as Hsp40; BAG-1; the Hsc70-interacting protein, Hip; and the Hsc70-Hsp90-organizing protein, Hop. " 03/01/1998 - "The regulation of the chaperone activity of the heat shock cognate Hsc70 protein in the mammalian cell involves a cooperation with chaperone cofactors such as Hsp40, the Hsp70-interacting protein Hip, and the Hsc70/Hsp90-organizing protein Hop. " 08/04/1995 - "Heat shock factor-1 and the heat shock cognate 70 protein associate in high molecular weight complexes in the cytoplasm of NIH-3T3 cells." Order ALL the reference details at left...
3.	Neoplasms (Cancer) 03/01/2004 - "Tumors with weak (+) HSC70 protein staining were more frequent in the carriers of the polymorphic 1541-1542delGT allele than in the homozygotes of the major allele (20% vs. 6%, P=0.05 by Fisher's exact test). " 11/15/1993 - "70 kDa heat shock cognate protein is a transformation-associated antigen and a possible target for the host's anti-tumor immunity." Order ALL the reference details at left...
4.	Anoxia (Hypoxia) 07/01/2006 - "[HSC70 protein of human blood mononuclears as a sign of adaptation under normobaric hypoxia training]" 10/31/2003 - "Hsc70 message and subcellular distribution of Hsc70 protein were unaffected by chronic hypoxia. " Order ALL the reference details at left...
5.	Breast Neoplasms (Breast Cancer) 09/01/2001 - "CONCLUSION: Antisense hsc70 RNA is able to lower the hsc70 protein level and significantly increase the instability of mutant p53 protein in MCF7/Adr human breast cancer cells." Order ALL the reference details at left...

Related Drugs and Biologics

1.	geranylgeranylacetone (teprenone)
2.	Messenger RNA (mRNA)
3.	Macromolecular Substances
4.	Small Nucleolar RNA (snoRNA)
5.	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)
6.	Complementary DNA (cDNA)
7.	Ribosomal RNA
8.	RNA (Ribonucleic Acid)
9.	Proteins (Proteins, Gene)
10.	Heat-Shock Proteins (Heat-Shock Protein)

Related Therapies and Procedures

1.	Injections

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