Sulfite Oxidase

A MOLYBDENUM requiring enzyme that catalyzes the terminal reaction in the oxidative degradation of SULFUR AMINO ACIDS with the formation of a sulfate. A deficiency of sulfite oxidase results in sulfocysteinuria.

Also Known As:

Networked: 93 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Schwarz, Guenter: 8 articles (01/2022 - 05/2010)
2.	Sass, Jörn Oliver: 5 articles (01/2012 - 11/2002)
3.	Reiss, Jochen: 5 articles (08/2010 - 12/2002)
4.	Kaczmarek, Alexander Tobias: 3 articles (01/2022 - 01/2019)
5.	Santamaria-Araujo, José Angel: 3 articles (01/2022 - 06/2004)
6.	Arjune, Sita: 3 articles (01/2021 - 01/2012)
7.	Bender, Daniel: 2 articles (01/2022 - 01/2019)
8.	Cirak, Sebahattin: 2 articles (01/2022 - 01/2019)
9.	Sagi, Moshe: 2 articles (01/2022 - 05/2007)
10.	Akiba, Jun: 2 articles (01/2021 - 09/2019)

Related Diseases

1.	Sulfite oxidase deficiency 01/01/2022 - "Isolated sulfite oxidase deficiency (ISOD) is a rare recessive and infantile lethal metabolic disorder, which is caused by functional loss of sulfite oxidase (SO) due to mutations of the SUOX gene. " 01/01/2021 - "Isolated sulfite oxidase deficiency (ISOD) is a rare autosomal recessive neuro-metabolic disorder caused by a mutation in the sulfite oxidase (SUOX) gene situated on chromosome 12. " 12/23/2019 - "Isolated sulfite oxidase deficiency (ISOD) is an autosomal recessive disorder caused by a deficiency of sulfite oxidase, which is encoded by the sulfite oxidase gene (SUOX). " 01/01/2019 - "Impaired mitochondrial maturation of sulfite oxidase in a patient with severe sulfite oxidase deficiency." 09/01/2014 - "Several point mutations in the gene of human sulfite oxidase (hSO) result in isolated sulfite oxidase deficiency, an inherited metabolic disorder. "
2.	Hypoxia (Hypoxemia) 11/30/2023 - "Replacement of molybdenum with tungsten or knockdown of sulfite oxidase expression in astrocytes blocks hypoxia-induced NO production by these glial cells and reduces the cerebrovascular response to hypoxia. " 11/30/2023 - "Astrocytes display high expression of the molybdenum-cofactor-containing mitochondrial enzyme sulfite oxidase, which can catalyze nitrite reduction in hypoxia. " 01/01/2017 - "To date, all the four known human molybdenum-containing enzymes, xanthine oxidase, aldehyde oxidase, sulfite oxidase, and mitochondrial amidoxime-reducing component, have been shown to function as nitrite reductases under hypoxia by biochemical, cellular, or animal studies. "
3.	Sclerosing Cholangitis 05/02/2018 - "In a recent study we had evidence that sulphite oxidase (SO) may be a relevant autoantigen in primary sclerosing cholangitis (PSC). " 05/02/2018 - "Sulphite oxidase (SO) - a mitochondrial autoantigen as target for humoral and cellular immune reactions in primary sclerosing cholangitis."
4.	Molybdenum cofactor deficiency 08/01/2020 - "To define the phenotypic spectrum of isolated sulfite oxidase (ISOD) and molybdenum cofactor deficiency (MoCD), aiming to promote timely diagnosis and assist in future clinical trial design. " 08/01/2020 - "Delineating the phenotypic spectrum of sulfite oxidase and molybdenum cofactor deficiency." 01/01/2013 - "Molybdenum cofactor deficiency (MoCD) is a rare inherited metabolic disorder characterized by severe and progressive neurologic damage mainly caused by the loss of sulfite oxidase activity. " 11/01/2012 - "Urinary AASA excretion is elevated in patients with molybdenum cofactor deficiency and isolated sulphite oxidase deficiency." 01/01/2012 - "Molybdenum cofactor deficiency (MoCD) is a rare inherited metabolic disorder characterized by severe and progressive neurological damage mainly caused by the loss of sulfite oxidase activity. "
5.	Seizures (Absence Seizure) 11/01/2005 - "Isolated sulphite oxidase deficiency (ISOD) is a rare autosomal recessive inborn error of metabolism, which may present at birth with intractable seizures (often of prenatal onset) and severe neurological abnormalities. " 08/01/2010 - "Functional deficiencies of sulfite oxidase: Differential diagnoses in neonates presenting with intractable seizures and cystic encephalomalacia." 09/01/1997 - "Isolated sulphite oxidase deficiency is a rare metabolic disorder characterised by neurological abnormalities, lens subluxation and seizures. " 01/01/2004 - "A patient with isolated sulphite oxidase deficiency presented with seizures at 12 h of life and followed a severe course, dying at 10 months of age. " 12/01/1998 - "Molybdenum cofactor (MoCo) deficiency is a rare and devastating disease resulting in neonatal seizures and other neurological symptoms identical to those of sulphite oxidase deficiency. "

Related Drugs and Biologics

1.	molybdenum trioxide
2.	Enzymes
3.	Aldehyde Oxidase
4.	Molybdenum
5.	Xanthine Oxidase
6.	Nitrite Reductases (Nitrite Reductase)
7.	Autoantigens
8.	amidoxime
9.	Xanthine Dehydrogenase
10.	molybdopterin (molybdenum cofactor)

Related Therapies and Procedures

1.	Therapeutics
2.	Lenses