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Glycine Dehydrogenase (Decarboxylating)

A PYRIDOXAL PHOSPHATE dependent enzyme that catalyzes the decarboxylation of GLYCINE with the transfer of an aminomethyl group to the LIPOIC ACID moiety of the GLYCINE DECARBOXYLASE COMPLEX H-PROTEIN. Defects in P-protein are the cause of non-ketotic hyperglycinemia. It is one of four subunits of the glycine decarboxylase complex.
Also Known As:
Glycine Cleavage System P-Protein; Glycine Decarboxylase; Glycine Decarboxylase Complex P-Protein; P-protein, Glycine Decarboxylase; Decarboxylase P-protein, Glycine; Decarboxylase, Glycine; Glycine Cleavage System P Protein; Glycine Decarboxylase Complex P Protein; Glycine Decarboxylase P-protein; P protein, Glycine Decarboxylase
Networked: 25 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Matsubara, Y: 2 articles (04/2005 - 03/2000)
2. Kure, S: 2 articles (04/2005 - 03/2000)
3. Cantor, Jason R: 1 article (04/2015)
4. Chudnovsky, Yakov: 1 article (04/2015)
5. Vander Heiden, Matthew G: 1 article (04/2015)
6. Gui, Dan Y: 1 article (04/2015)
7. Snuderl, Matija: 1 article (04/2015)
8. Pacold, Michael E: 1 article (04/2015)
9. Birsoy, Kivanc: 1 article (04/2015)
10. Kang, Seong Woo: 1 article (04/2015)

Related Diseases

1. Nonketotic Hyperglycinemia
2. B-Cell Lymphoma (Lymphoma, B Cell)
3. Tics (Tic)
4. Neoplasms (Cancer)
5. Infection

Related Drugs and Biologics

1. glycine cleavage system
2. Complementary DNA (cDNA)
3. Enzymes
4. Aminomethyltransferase (Glycine Synthase)
5. Glycine Hydroxymethyltransferase (Serine Hydroxymethyltransferase)
6. Oxidoreductases
7. Glycine encephalopathy
8. Phosphoglycerate Dehydrogenase (Dehydrogenase, Phosphoglycerate)
9. Hydroxypyruvate Reductase
10. Photosystem I Protein Complex (Photosystem I)