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Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)

An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.
Also Known As:
Interferon Regulatory Factor 3; IFN-Regulatory Factor 3; IFN Regulatory Factor 3; IRF 3 Transcription Factor; Transcription Factor, IRF-3; IRF-3 Transcription Factor
Networked: 439 relevant articles (5 outcomes, 18 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Gale, Michael: 12 articles (02/2014 - 07/2004)
2. Zhou, Guo-Ping: 10 articles (03/2018 - 10/2010)
3. Hiscott, John: 10 articles (06/2009 - 06/2002)
4. Akira, Shizuo: 9 articles (01/2018 - 10/2004)
5. Grandvaux, Nathalie: 9 articles (01/2014 - 06/2002)
6. Jin, Rui: 8 articles (03/2018 - 04/2011)
7. Fujita, Takashi: 7 articles (01/2016 - 06/2002)
8. Lin, Rongtuan: 7 articles (06/2009 - 06/2002)
9. Ren, Wei: 6 articles (01/2016 - 10/2010)
10. Xu, Hua-Guo: 6 articles (01/2016 - 10/2010)

Related Diseases

1. Infections
2. Viremia
3. Multiple Sclerosis
4. Weight Gain
5. Thyroiditis

Related Drugs and Biologics

1. Interferons
2. Messenger RNA (mRNA)
3. Toll-Like Receptor 3
4. Transforming Growth Factor beta (TGF-beta)
5. Cannabinoids
6. Vaccines
7. Quercetin
8. phenyl methimazole
9. Transcription Factors (Transcription Factor)
10. Phosphotransferases (Kinase)

Related Therapies and Procedures

1. Punctures
2. Ligation
3. Intraperitoneal Injections