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Interferon Regulatory Factors

A family of transcription factors that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to control GENE expression. IRF proteins bind specific DNA sequences such as interferon-stimulated response elements, interferon regulatory elements, and the interferon consensus sequence.
Also Known As:
IRF Transcription Factors; Factor, Interferon Regulatory; Regulatory Factor, Interferon; Transcription Factors, IRF; Interferon Regulatory Factor
Networked: 701 relevant articles (5 outcomes, 59 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Barnes, Betsy J: 11 articles (01/2020 - 03/2008)
2. Schutte, Brian C: 11 articles (03/2016 - 01/2003)
3. Syvänen, Ann-Christine: 9 articles (01/2013 - 03/2005)
4. Murray, Jeffrey C: 8 articles (05/2014 - 01/2003)
5. Dunnwald, Martine: 7 articles (01/2020 - 09/2010)
6. Rönnblom, Lars: 7 articles (01/2013 - 03/2005)
7. Sigurdsson, Snaevar: 7 articles (01/2013 - 03/2005)
8. Niewold, Timothy B: 6 articles (01/2022 - 08/2008)
9. Gale, Michael: 6 articles (01/2021 - 09/2008)
10. Hua, Shucheng: 6 articles (10/2019 - 01/2017)

Related Diseases

1. Infections
2. Multiple Myeloma
3. Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
4. Diabetic Nephropathies (Diabetic Nephropathy)
5. Systemic Lupus Erythematosus (Libman-Sacks Disease)

Related Drugs and Biologics

1. Interferons
2. Proteins (Proteins, Gene)
3. Interferon Type I
4. Toll-Like Receptors (Toll-Like Receptor)
5. Virulence Factors (Pathogenicity Factors)
6. Immunomodulating Agents
7. aloe emodin
8. Transcription Factors (Transcription Factor)
9. Cytokines
10. NF-kappa B (NF-kB)

Related Therapies and Procedures

1. Therapeutics
2. Liver Transplantation
3. Immunotherapy
4. Drug Therapy (Chemotherapy)