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Interferon-Stimulated Gene Factor 3

A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.
Also Known As:
ISGF3 Factor; Transcription Factor ISGF3; IFN Stimulated Gene Factor 3 Complex; ISGF3, Transcription Factor; Interferon Stimulated Gene Factor 3; Transcription Factor, ISGF3; IFN-Stimulated Gene Factor 3 Complex; ISGF3 Transcription Factor
Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Hackett, Scott J: 1 article (02/2013)
2. Young, Dan F: 1 article (02/2013)
3. Goodbourn, Stephen: 1 article (02/2013)
4. Mohamad, Siti M B: 1 article (02/2013)
5. Morgan, Neil V: 1 article (02/2013)
6. Valappil, Manoj: 1 article (02/2013)
7. Dickinson, Paul: 1 article (02/2013)
8. Ghazal, Peter: 1 article (02/2013)
9. Randall, Richard E: 1 article (02/2013)
10. Hambleton, Sophie: 1 article (02/2013)

Related Diseases

1. Infection
2. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
3. Leukemia
4. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Interferon-alpha (Interferon Alfa)
2. DNA (Deoxyribonucleic Acid)
3. NF-kappa B (NF-kB)
4. Proteins (Proteins, Gene)
5. KT 1 (KT-1)