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Interferon-Stimulated Gene Factor 3

A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.
Also Known As:
ISGF3 Factor; Transcription Factor ISGF3; IFN Stimulated Gene Factor 3 Complex; ISGF3, Transcription Factor; Interferon Stimulated Gene Factor 3; Transcription Factor, ISGF3; IFN-Stimulated Gene Factor 3 Complex; ISGF3 Transcription Factor
Networked: 12 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Alvarado, Gloria: 1 article (12/2022)
2. Horvath, Curt M: 1 article (12/2022)
3. Lenoir, Jessica J: 1 article (12/2022)
4. Parisien, Jean-Patrick: 1 article (12/2022)
5. Ng, Siew Kit: 1 article (01/2018)
6. Paul, Alvin: 1 article (01/2018)
7. Tang, Thean Hock: 1 article (01/2018)
8. Massie, Tammy: 1 article (10/2016)
9. Massie, Tristan: 1 article (10/2016)
10. Novatt, Hilary: 1 article (10/2016)

Related Diseases

1. Virus Diseases (Viral Diseases)
2. Infections
3. Bites and Stings (Sting)
4. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Transcription Factors (Transcription Factor)
2. Interferons
3. Interferon Type I
4. Interferon-alpha (Interferon Alfa)
5. NF-kappa B (NF-kB)
6. DNA (Deoxyribonucleic Acid)
7. gamma Subunit Interferon-Stimulated Gene Factor 3 (Interferon Stimulated Gene Factor 3, gamma Subunit)
8. Proteins (Proteins, Gene)
9. Antiviral Agents (Antivirals)
10. cyclic guanosine monophosphate-adenosine monophosphate