A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.
Also Known As:
ISGF3 Factor; Transcription Factor ISGF3; IFN Stimulated Gene Factor 3 Complex; ISGF3, Transcription Factor; Interferon Stimulated Gene Factor 3; Transcription Factor, ISGF3; IFN-Stimulated Gene Factor 3 Complex; ISGF3 Transcription Factor