Octamer Transcription Factor-2 (Octamer Transcription Factor 2)

An octamer transcription factor expressed primarily in B-LYMPHOCYTES and the developing CENTRAL NERVOUS SYSTEM that regulates GENETIC TRANSCRIPTION of IMMUNOGLOBULIN GENES.

Also Known As:

Octamer Transcription Factor 2; Transcription Factor Oct 2; Oct 2 Transcription Factor; Oct-2, Transcription Factor; Transcription Factor, Oct-2; Transcription Factor-2, Octamer; Oct-2 Transcription Factor; Transcription Factor Oct-2

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Inflammation (Inflammations) 02/02/1996 - "Induction of the Oct-2 transcription factor in primary sensory neurons during inflammation is nerve growth factor-dependent."
2.	Infections 03/11/1994 - "Here we show that the ectopic expression of neuronal isoforms of the octamer/TAATGARAT-binding transcription factor Oct-2 in permissive BHK cells represses IE gene expression following HSV infection and inhibits the viral lytic cycle whereas the B lymphocyte isoform of Oct-2 does not have this effect. "
3.	Herpes Simplex 03/11/1994 - "Inhibition of herpes simplex virus infection by ectopic expression of neuronal splice variants of the Oct-2 transcription factor."

Related Drugs and Biologics

1.	Nerve Growth Factor (NGF)
2.	Protein Isoforms (Isoforms)