|1.||Finkelman, Fred D: 3 articles (05/2007 - 08/2006)|
|2.||Rothenberg, Marc E: 3 articles (05/2007 - 02/2003)|
|3.||Li, Feng: 2 articles (01/2015 - 03/2012)|
|4.||Zhang, Yan: 2 articles (02/2014 - 03/2012)|
|5.||Keegan, Achsah D: 2 articles (09/2013 - 01/2011)|
|6.||McKenzie, Andrew N J: 2 articles (08/2013 - 05/2009)|
|7.||Brombacher, Frank: 2 articles (08/2013 - 01/2007)|
|8.||Anthony, Robert M: 2 articles (08/2013 - 07/2008)|
|9.||Wills-Karp, Marsha: 2 articles (01/2013 - 08/2006)|
|10.||Hopkin, Julian M: 2 articles (01/2013 - 06/2009)|
06/01/2015 - "The tumor cells in both components showed the nuclear expression of STAT6 protein, indicating the diagnostic value of these examinations. "
02/01/2015 - "Immunohistochemically, the tumor cells were diffusely positive for signal transducer and activator of transcription 6 (STAT6) but negative for CD34. "
03/01/2012 - "Signal transducer and activator of transcription 6 (Stat6) is critical in Th2 polarization of immune cells and active Stat6 activity has been suggested in anti-tumor immunity in animal models. "
02/01/2004 - "Signal transducer and activator of transcription 6 (Stat6) and CD1: inhibitors of immunosurveillance against primary tumors and metastatic disease."
02/15/2003 - "An analysis of the T cells from tumor-bearing STAT6-/- mice revealed that they contained a population primed by a peptide (STAT6(531-539)) of the STAT6 protein expressed in 4T1. "
|2.||Neoplasm Metastasis (Metastasis)
02/03/2003 - "Clearance of lung metastases by the Th2 cells was found to be totally dependent on the eosinophil chemokine, eotaxin, and partially dependent on the transcription activator signal transducer and activator of transcription 6 (STAT6), with degranulating eosinophils within the tumors inducing tumor regression. "
|3.||Asthma (Bronchial Asthma)
01/01/2013 - "Signal transducer and activator of transcription 6 polymorphism and asthma risk: a meta-analysis."
01/01/2011 - "The signal transducer and activator of transcription 6 (STAT6) expression in lung epithelial cells plays a pivotal role in asthma pathogenesis. "
09/01/2004 - "In this paper, we report for the first time the results of an investigation on the association of signal transducer and activator of transcription 6 (STAT6) with asthma in the Indian population. "
09/01/2004 - "Signal transducer and activator of transcription 6 haplotypes and asthma in the Indian population."
05/01/2003 - "Dissociation of T helper type 2 cytokine-dependent airway lesions from signal transducer and activator of transcription 6 signalling in experimental chronic asthma."
08/01/2007 - "Adoptive T-cell transfer experiments were further performed to determine whether signal transducer and activator of transcription 6 (STAT6) was required for cell recruitment and allergic inflammation. "
06/01/2009 - "Signal transducer and activator of transcription 6 (STAT6) expression in lung epithelial cells plays a central role in asthma pathogenesis, with its activation driving the development of airway hyper-reactivity and local inflammation. "
01/01/2012 - "Mice that express a constitutively active Signal Transducer and Activator of Transcription 6 (STAT6VT) have increased Th2 cells and a predisposition to allergic inflammation were used in these studies, they demonstrate that topical treatment with the irritant sodium lauryl sulfate (SLS) caused increased transepidermal water loss and epidermal thickening in STAT6VT mice over similarly treated wild-type mice. "
01/08/2014 - "Although there are many reports on the activation and roles of signal transducer and activator of transcription (STAT) proteins (STAT1, STAT3, and STAT5) during hyperexcitation in the neuron and inflammation occurring following I/R, the temporal and spatial activation of STAT6 protein in the ischemic cortex still remain elusive. "
06/15/2009 - "These data show that targeting the key transcription factor STAT6 by siRNA effectively blocks the development of cardinal features of allergic airway disease, like allergen-induced airway inflammation and AHR. "
|5.||Breast Neoplasms (Breast Cancer)
02/01/2000 - "Our findings thus suggest that the multiple pathways downstream of IRS-1 and IRS-2 must act in cooperation with the IL-4-specific transcription factor Stat6 to mediate the induction of 31beta-HSD type 1 gene expression in ZR-75-1 human breast cancer cells."
01/01/2015 - "Furthermore, IL13Ralpha2 silencing was associated with enhanced IL-13-mediated phosphorylation of signal transducer and activator of transcription 6 (STAT6) and impaired migratory ability of metastatic breast cancer cells. "
09/28/2013 - "Furthermore, the IL-4-induced tyrosine phosphorylation of the transcription factor STAT6 was shown to protect breast cancer cells from apoptosis. "
02/01/2013 - "The signal transducer and activator of transcription 6 (Stat6), a member of the family of DNA-binding proteins, has been identified as a critical cell differentiation modulator in breast cancer cells. "
05/14/2007 - "The expression of phosphorylated signal transducer and activator of transcription 6 in breast cancer cells suggests that IL-13 actually delivers signals to cancer cells. "
|2.||Messenger RNA (mRNA)
|3.||Interleukin-4 (Interleukin 4)
|4.||Sodium Dodecyl Sulfate (Sodium Lauryl Sulfate)
|7.||Nitric Oxide (Nitrogen Monoxide)
|8.||Hyaluronic Acid (Hyaluronan)
|10.||aldehyde dehydrogenase 1