HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)

A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.
Also Known As:
Signal Transducer and Activator of Transcription 3; APRF Transcription Factor; Acute-Phase Response Factor; IL6-Response Factor; LIF-Response Factor; STAT3 Protein; STAT3a Transcription Factor; STAT3b Transcription Factor; Stat3alpha Transcription Factor; Stat3beta Transcription Factor; Acute Phase Response Factor; IL6 Response Factor; LIF Response Factor; Response Factor, Acute-Phase; Transcription Factor, APRF; Transcription Factor, STAT3; Transcription Factor, STAT3a; Transcription Factor, STAT3b; Transcription Factor, Stat3alpha; Transcription Factor, Stat3beta
Networked: 2795 relevant articles (46 outcomes, 261 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Lin, Jiayuh: 41 articles (01/2021 - 01/2002)
2. Sethi, Gautam: 31 articles (01/2022 - 05/2007)
3. Ahn, Kwang Seok: 28 articles (01/2022 - 03/2009)
4. Li, Chenglong: 26 articles (01/2021 - 07/2009)
5. Frank, David A: 20 articles (01/2022 - 06/2005)
6. Zhang, Wei: 16 articles (05/2021 - 01/2008)
7. Kumar, Alan Prem: 16 articles (12/2020 - 07/2010)
8. Jove, Richard: 14 articles (05/2016 - 03/2002)
9. Turkson, James: 14 articles (05/2014 - 03/2002)
10. Kim, Sung-Hoon: 13 articles (06/2022 - 03/2011)

Related Diseases

1. Neoplasms (Cancer)
2. Inflammation (Inflammations)
3. Fibrosis (Cirrhosis)
4. Ischemia
5. Neoplasm Metastasis (Metastasis)

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Interleukin-6 (Interleukin 6)
3. Transcription Factors (Transcription Factor)
4. Interleukin-22 (IL-22)
5. Cytokines
6. Janus Kinase 2
7. Janus Kinases
8. STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)
9. Cisplatin (Platino)
10. Small Interfering RNA (siRNA)

Related Therapies and Procedures

1. Radiotherapy
2. Electroacupuncture
3. Intravenous Administration
4. Oral Administration
5. Therapeutics