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Deep Hypothermia Induced Circulatory Arrest

A technique to arrest the flow of blood by lowering BODY TEMPERATURE to about 20 degrees Centigrade, usually achieved by infusing chilled perfusate. The technique provides a bloodless surgical field for complex surgeries.
Also Known As:
Circulatory Arrest, Deep Hypothermia Induced; Deep Hypothermic Circulatory Arrest
Networked: 567 relevant articles (22 outcomes, 43 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1. Gaynor, J William: 14 articles (01/2022 - 03/2003)
2. Wang, Guyan: 8 articles (01/2022 - 12/2006)
3. Nicolson, Susan C: 7 articles (01/2022 - 11/2005)
4. Spray, Thomas L: 7 articles (01/2018 - 03/2003)
5. Jonas, Richard A: 7 articles (03/2017 - 01/2002)
6. Li, Jun: 6 articles (01/2022 - 01/2019)
7. Licht, Daniel J: 6 articles (01/2022 - 07/2015)
8. Yang, Lijing: 6 articles (01/2022 - 01/2019)
9. Yu, Cuntao: 6 articles (01/2021 - 12/2013)
10. Bavaria, Joseph E: 6 articles (01/2018 - 04/2002)

Related Diseases

1. Brain Injuries (Brain Injury)
2. Thrombosis (Thrombus)
3. Neoplasms (Cancer)
4. Intracranial Aneurysm (Cerebral Aneurysm)
5. Hypothermia
03/01/2016 - "In the late 1980s, when deep hypothermic circulatory arrest was the standard operative strategy for aortic surgery, selective cerebral perfusion, as an adjunct to deep hypothermia, made possible excellent neuroprotection and improved overall outcome. "
04/01/2020 - "From December 2014 to February 2017, 89 patients were enrolled in this study, 52 of whom underwent conventional deep hypothermic circulatory arrest (DHCA, 24.2±0.71 °C) using the antegrade cerebral perfusion surgical procedure (Group A) and 37 of whom underwent the "arch-first" technique with moderate (27.4±1.1 °C) systemic hypothermia during antegrade cerebral perfusion (Group B). "
10/01/1998 - "To analyze studies of neurological injury after open-heart surgery in infants and children and to discuss the effects of cardiopulmonary bypass, hypothermia and deep hypothermic circulatory arrest on cerebral blood flow, cerebral metabolism and brain temperature. "
01/01/1996 - "To assess the diagnostic accuracy of this modality, a study was conducted between 1991 and 1994, recording SEPs in 287 consecutive patients undergoing cardiac and aortic surgery using cardiopulmonary bypass (CPB) with moderate hypothermia or deep hypothermic circulatory arrest. "
01/01/2022 - "Neonatal swine (n = 25) were randomized to continuous deep hypothermic cardiopulmonary bypass (DH-CPB, n = 7), deep hypothermic circulatory arrest (DHCA, n = 7), selective cerebral perfusion (SCP, n = 7) at deep hypothermia, or normothermic cardiopulmonary bypass (control, n = 4). "

Related Drugs and Biologics

1. Oxygen (Dioxygen)
2. Moxifloxacin (Avelox)
3. Aprotinin (Trasylol)
4. Anesthetics (Anesthetic Agents)
5. Activating Transcription Factor 6
6. Sodium-Hydrogen Exchangers
7. Phenoxybenzamine
8. Lipopolysaccharides
9. coenzyme Q10 (CoQ10)
10. Heparin (Liquaemin)

Related Therapies and Procedures

1. Cardiopulmonary Bypass (Heart-Lung Bypass)
2. Extracorporeal Circulation
3. Sternotomy
4. Rewarming
5. Nephrectomy