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NFATC Transcription Factors

A family of transcription factors characterized by the presence of highly conserved calcineurin- and DNA-binding domains. NFAT proteins are activated in the CYTOPLASM by the calcium-dependent phosphatase CALCINEURIN. They transduce calcium signals to the nucleus where they can interact with TRANSCRIPTION FACTOR AP-1 or NF-KAPPA B and initiate GENETIC TRANSCRIPTION of GENES involved in CELL DIFFERENTIATION and development. NFAT proteins stimulate T-CELL activation through the induction of IMMEDIATE-EARLY GENES such as INTERLEUKIN-2.
Also Known As:
NF-AT Proteins; NF-AT3 Protein; NF-AT4 Protein; NF-ATc1 Protein; NFAT Proteins; NFAT-1 Protein; NFAT-2 Protein; NFAT1 Protein; NFAT2 Protein; NFAT3 Protein; NFAT4 Protein; NFAT5 Protein; NFATC Proteins; NFATC1 Protein; NFATC1 Transcription Factor; NFATC2 Protein; NFATC2 Transcription Factor; NFATC3 Protein; NFATC3 Transcription Factor; NFATC4 Protein; NFATC4 Transcription Factor; NFATL1 Protein; NFATx Protein; NFATz Protein; Nuclear Factor of Activated T-Cells 5 Protein; Nuclear Factor of Activated T-Cells, Cytoplasmic; Nuclear Factor of Activated T-Cells, Cytoplasmic 1 Protein; Nuclear Factor of Activated T-Cells, Cytoplasmic 2 Protein; Nuclear Factor of Activated T-Cells, Cytoplasmic 3 Protein; Nuclear Factor of Activated T-Cells, Cytoplasmic 4 Protein; OREBP Protein; Osmotic Response Element Binding Protein; TonEBP Protein; Tonicity-Responsive Enhancer-Binding Protein; Transcription Factor NF-AT; Factor, NFATC1 Transcription; Factor, NFATC2 Transcription; Factor, NFATC3 Transcription; NF AT Proteins; NF AT3 Protein; NF AT4 Protein; NF ATc1 Protein; NF-AT, Transcription Factor; NFAT 1 Protein; NFAT 2 Protein; Nuclear Factor of Activated T Cells 5 Protein; Nuclear Factor of Activated T Cells, Cytoplasmic; Nuclear Factor of Activated T Cells, Cytoplasmic 1 Protein; Nuclear Factor of Activated T Cells, Cytoplasmic 2 Protein; Nuclear Factor of Activated T Cells, Cytoplasmic 3 Protein; Nuclear Factor of Activated T Cells, Cytoplasmic 4 Protein; Nuclear Factors of Activated T Cells; Tonicity Responsive Enhancer Binding Protein; Transcription Factor NF AT; Transcription Factor, NFATC1; Transcription Factor, NFATC2; Transcription Factor, NFATC3; Transcription Factor, NFATC4; Transcription Factors, NFATC; NFAT Transcription Factor 1; NFAT Transcription Factor 2; NFAT Transcription Factor 3; NFAT Transcription Factor 4; NFAT Transcription Factor 5; Nuclear Factors of Activated T-Cells
Networked: 73 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Ellenrieder, Volker: 3 articles (01/2016 - 08/2011)
2. Lehr, Hans A: 3 articles (09/2012 - 09/2008)
3. Neurath, Markus F: 3 articles (09/2012 - 09/2008)
4. Koenig, Alexander: 2 articles (01/2016 - 02/2015)
5. Hessmann, Elisabeth: 2 articles (01/2016 - 02/2015)
6. Billadeau, Daniel D: 2 articles (01/2016 - 02/2015)
7. Zhang, Jin-San: 2 articles (01/2016 - 02/2015)
8. Chen, Nai-Ming: 2 articles (01/2016 - 02/2015)
9. Singh, Shiv K: 2 articles (02/2015 - 08/2011)
10. Singh, Garima: 2 articles (02/2015 - 08/2011)

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Related Drugs and Biologics

1. Calcineurin
2. NF-kappa B (NF-kB)
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6. Messenger RNA (mRNA)
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