A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.
Also Known As:
Alpha-Stathmin; Beta-Stathmin; Lap18 Protein; Leukemia-Associated Phosphoprotein p18; Metablastin; Oncoprotein 18; Op18 Phosphoprotein; Op18a Protein; Op18b Protein; Phosphoprotein p18; Phosphoprotein p19; Prosolin; Alpha Stathmin; Beta Stathmin; Leukemia Associated Phosphoprotein p18; Phosphoprotein, Op18; p18, Leukemia-Associated Phosphoprotein; p18, Phosphoprotein; p19, Phosphoprotein