The larger fragment generated from the cleavage of C5 by C5 CONVERTASE that yields COMPLEMENT C5A and C5b (beta chain + alpha' chain, the residual alpha chain, bound by disulfide bond). C5b remains bound to the membrane and initiates the spontaneous assembly of the late complement components to form C5b-8-poly-C9, the MEMBRANE ATTACK COMPLEX.
Also Known As:
C5b Complement; Complement 5b; Complement Component 5b; C5b, Complement; Complement, C5b; Component 5b, Complement; Complement C 5b
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