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Retinoblastoma-Like Protein p107

A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. It contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.
Also Known As:
RBL1 Protein; Retinoblastoma Like Protein p107; p107 Tumor Suppressor Protein; Retinoblastoma Like Protein 1; p107, Retinoblastoma-Like Protein; Retinoblastoma-Like Protein 1
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Bio-Agent Context: Research Results