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Crk-Associated Substrate Protein

Crk-associated substrate was originally identified as a highly phosphorylated 130 kDa protein that associates with ONCOGENE PROTEIN CRK and ONCOGENE PROTEIN SRC. It is a signal transducing adaptor protein that undergoes tyrosine PHOSPHORYLATION in signaling pathways that regulate CELL MIGRATION and CELL PROLIFERATION.
Also Known As:
BCAR1 Protein; Breast Cancer Anti-Estrogen Resistance 1 Protein; CKRAS Protein; Crk-Associated Substrate; p130 Cas Protein; p130 Crk-Associated Substrate; p130Cas Protein; Breast Cancer Anti Estrogen Resistance 1 Protein; Cas Protein, p130; Crk Associated Substrate; Crk Associated Substrate Protein; Crk-Associated Substrate, p130; Substrate Protein, Crk-Associated; Substrate, p130 Crk-Associated; p130 Crk Associated Substrate
Networked: 32 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Kumbrink, Joerg: 3 articles (05/2015 - 02/2012)
2. Kirsch, Kathrin H: 3 articles (05/2015 - 02/2012)
3. Dorssers, Lambert C J: 3 articles (09/2004 - 08/2004)
4. Span, Paul N: 3 articles (09/2004 - 08/2004)
5. Grebenchtchikov, Nicolai: 3 articles (09/2004 - 08/2004)
6. Geurts-Moespot, Anneke: 3 articles (09/2004 - 08/2004)
7. Foekens, John A: 3 articles (09/2004 - 08/2004)
8. Brinkman, Arend: 3 articles (09/2004 - 08/2004)
9. van der Flier, S: 3 articles (07/2001 - 01/2000)
10. Dorssers, L C: 3 articles (07/2001 - 01/2000)

Related Diseases

1. Colorectal Neoplasms (Colorectal Cancer)
2. Prostatic Neoplasms (Prostate Cancer)
3. Neoplasms (Cancer)
4. Breast Neoplasms (Breast Cancer)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Tyrosine (L-Tyrosine)
2. Focal Adhesion Protein-Tyrosine Kinases
3. Paxillin
4. Tamoxifen
5. Estrogen Receptor Modulators (Antiestrogen)
6. Phosphotransferases (Kinase)
7. Estrogens (Estrogen)
8. Integrin beta3 (GPIIIa)
9. Plasminogen Activator Inhibitor 1
10. Interleukin-8 (Interleukin 8)