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Retinoblastoma-Like Protein p130

A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and E2F5 TRANSCRIPTION FACTOR. RBL2 also interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.
Also Known As:
RBL2 Protein; Retinoblastoma Like Protein p130; Retinoblastoma Like Protein 2; p130, Retinoblastoma-Like Protein; Retinoblastoma-Like Protein 2
Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. DeCaprio, J A: 1 article (07/2014)

Related Diseases

1. Retinoblastoma (Glioblastoma, Retinal)
2. Neoplasms (Cancer)

Related Drugs and Biologics

1. Proteasome Endopeptidase Complex (Proteasome)