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Complement C4b-Binding Protein

A serum protein that regulates the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It binds as a cofactor to COMPLEMENT FACTOR I which then hydrolyzes the COMPLEMENT C4B in the CLASSICAL PATHWAY C3 CONVERTASE (C4bC2a).
Also Known As:
C4b-Binding Protein; C4b-C3b Inactivator Cofactor; C4bC3bINA-Cofactor; Complement 4b Binding Protein; Complement C3b-C4b Inactivator Cofactor; Complement Component 4b-Binding Protein; C4b Binding Protein; C4b C3b Inactivator Cofactor; C4b-Binding Protein, Complement; C4bC3bINA Cofactor; Cofactor, C4b-C3b Inactivator; Complement C3b C4b Inactivator Cofactor; Complement C4b Binding Protein; Complement Component 4b Binding Protein; Protein, C4b-Binding; Protein, Complement C4b-Binding
Networked: 91 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Blom, Anna M: 13 articles (11/2016 - 11/2005)
2. Blom, A M: 5 articles (10/2009 - 07/2001)
3. Battistelli, S: 4 articles (01/2008 - 01/2008)
4. Petrioli, R: 4 articles (01/2008 - 01/2008)
5. Stefanoni, M: 4 articles (01/2008 - 01/2008)
6. Ohtsuka, Masayuki: 3 articles (06/2021 - 10/2016)
7. Takano, Shigetsugu: 3 articles (06/2021 - 10/2016)
8. Martin, Myriam: 3 articles (11/2016 - 07/2009)
9. Furukawa, Katsunori: 2 articles (06/2021 - 02/2021)
10. Kuboki, Satoshi: 2 articles (06/2021 - 02/2021)

Related Diseases

1. Protein S Deficiency (Deficiency, Protein S)
2. Thrombosis (Thrombus)
3. Hepatocellular Carcinoma (Hepatoma)
4. HIV Infections (HIV Infection)
5. COVID-19

Related Drugs and Biologics

1. Protein S
2. Complement System Proteins (Complement)
3. Protein C
4. Complement Factor H (Factor H)
5. Complement Inactivating Agents
6. Proteins (Proteins, Gene)
7. Fibrinogen (Factor I)
8. Antigens
9. Anticoagulants
10. Biomarkers (Surrogate Marker)

Related Therapies and Procedures

1. Orthopedic Procedures
2. Blood Component Removal (Apheresis)
3. Glycemic Control