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Complement C4b-Binding Protein

A serum protein that regulates the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It binds as a cofactor to COMPLEMENT FACTOR I which then hydrolyzes the COMPLEMENT C4B in the CLASSICAL PATHWAY C3 CONVERTASE (C4bC2a).
Also Known As:
C4b-Binding Protein; C4b-C3b Inactivator Cofactor; C4bC3bINA-Cofactor; Complement 4b Binding Protein; Complement C3b-C4b Inactivator Cofactor; Complement Component 4b-Binding Protein; C4b Binding Protein; C4b C3b Inactivator Cofactor; C4b-Binding Protein, Complement; C4bC3bINA Cofactor; Cofactor, C4b-C3b Inactivator; Complement C3b C4b Inactivator Cofactor; Complement C4b Binding Protein; Complement Component 4b Binding Protein; Protein, C4b-Binding; Protein, Complement C4b-Binding
Networked: 73 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Blom, Anna M: 11 articles (06/2013 - 11/2005)
2. Blom, A M: 5 articles (10/2009 - 07/2001)
3. Atkinson, John P: 2 articles (06/2013 - 07/2011)
4. Martin, Myriam: 2 articles (04/2012 - 07/2009)
5. Niessen, Hans W M: 2 articles (12/2011 - 01/2008)
6. Kupreishvili, Koba: 2 articles (12/2011 - 01/2008)
7. Jarva, Hanna: 2 articles (01/2011 - 11/2005)
8. Meri, Seppo: 2 articles (01/2011 - 03/2010)
9. Ram, Sanjay: 2 articles (12/2008 - 11/2005)
10. Trouw, Leendert A: 2 articles (08/2008 - 01/2008)

Related Diseases

1. Protein S Deficiency (Deficiency, Protein S)
2. Infection
3. Inflammation
4. Thrombosis (Thrombus)
5. Pre-Eclampsia (Preeclampsia)

Related Drugs and Biologics

1. Protein S
2. Complement System Proteins (Complement)
3. Protein C
4. Antigens
5. Complement Factor H (Factor H)
6. Fibrinogen (Factor I)
7. Interleukin-6 (Interleukin 6)
8. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
9. Proteins (Proteins, Gene)
10. Acute-Phase Proteins (Acute-Phase Protein)

Related Therapies and Procedures

1. Blood Component Removal (Apheresis)