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E2F Transcription Factors

A family of basic helix-loop-helix transcription factors that control expression of a variety of GENES involved in CELL CYCLE regulation. E2F transcription factors typically form heterodimeric complexes with TRANSCRIPTION FACTOR DP1 or transcription factor DP2, and they have N-terminal DNA binding and dimerization domains. E2F transcription factors can act as mediators of transcriptional repression or transcriptional activation.
Also Known As:
E2F Proteins; Transcription Factor E2F; E2F, Transcription Factor; Transcription Factors, E2F
Networked: 244 relevant articles (0 outcomes, 14 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Lees, Jacqueline A: 6 articles (01/2010 - 12/2002)
2. Andrechek, Eran R: 4 articles (11/2015 - 08/2007)
3. Ohtani, Kiyoshi: 3 articles (09/2015 - 01/2009)
4. Ozono, Eiko: 3 articles (09/2015 - 01/2009)
5. Iwanaga, Ritsuko: 3 articles (09/2015 - 01/2009)
6. Pillai, Smitha: 3 articles (01/2014 - 02/2011)
7. Chellappan, Srikumar P: 3 articles (01/2014 - 02/2011)
8. Duronio, Robert J: 3 articles (11/2012 - 09/2007)
9. Knudsen, Erik S: 3 articles (12/2010 - 07/2007)
10. Lee, Eunice Y: 3 articles (01/2010 - 12/2002)

Related Diseases

1. Neoplasms (Cancer)
2. Retinoblastoma (Glioblastoma, Retinal)
3. Ovarian Neoplasms (Ovarian Cancer)
4. Breast Neoplasms (Breast Cancer)
5. Hyperplasia

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Cyclins
3. Transcription Factors (Transcription Factor)
4. Phosphotransferases (Kinase)
5. DNA (Deoxyribonucleic Acid)
6. Cyclin-Dependent Kinase Inhibitor p16
7. MicroRNAs (MicroRNA)
8. Interferon-gamma (Interferon, gamma)
9. Epidermal Growth Factor (EGF)
10. Retinoblastoma Protein

Related Therapies and Procedures

1. Lasers (Laser)
2. Transplants (Transplant)
3. Filtering Surgery
4. Photochemotherapy (Photodynamic Therapy)
5. Drug Therapy (Chemotherapy)