|1.||Nakagawa, Masahiro: 2 articles (06/2013 - 12/2004)|
|2.||Kurokawa, Mineo: 2 articles (06/2013 - 12/2004)|
|3.||Mitani, Kinuko: 2 articles (08/2012 - 12/2004)|
|4.||Speck, Nancy A: 2 articles (01/2011 - 11/2005)|
|5.||Abonante, Sergio: 1 article (06/2015)|
|6.||Cirillo, Francesca: 1 article (06/2015)|
|7.||Maggiolini, Marcello: 1 article (06/2015)|
|8.||Panno, Maria Luisa: 1 article (06/2015)|
|9.||Pellegrino, Michele: 1 article (06/2015)|
|10.||Vivacqua, Adele: 1 article (06/2015)|
|1.||Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/01/2007 - "In this study, we used structural equation models (SEMs) to construct genetic networks to model how specific single-nucleotide polymorphisms (SNPs) from two genes known to cause acute myeloid leukemia (AML) by somatic mutation, runt-related transcription factor 1 (RUNX1) and ets variant gene 6 (ETV6), affect expression levels of other genes and how RUNX1 and ETV6 are related to each other. "
11/15/2005 - "In addition, loss-of-function mutations in Runt-related transcription factor 1 (RUNX1) have been identified in sporadic cases of acute myeloid leukemia (AML) and in association with the familial platelet disorder with propensity to develop AML (FPD/AML). "
03/05/1999 - "c-fos promoter activity was induced by transient overexpression of acute myeloid leukemia 1 in Jurkat T-cells, but not by that of the short form of acute myeloid leukemia 1-MTG8, a chimeric acute myeloid leukemia 1 protein. "
10/01/2013 - "Translocations involving chromosome 21q22 are frequently observed in hematologic malignancies including acute myeloid leukemia (AML), most of which have been known to be involved in malignant transformation through transcriptional dysregulation of Runt-related transcription factor 1 (RUNX1) target genes. "
04/01/2011 - "Repression of vascular endothelial growth factor expression by the runt-related transcription factor 1 in acute myeloid leukemia."
01/01/2015 - "The purposes of this study were to investigate the possible molecular mechanisms of miR-18a regulating the permeability of blood-tumor barrier (BTB) via down-regulated expression and distribution of runt-related transcription factor 1 (RUNX1). "
01/11/2013 - "Runt-related transcription factor 1 (RUNX1) stimulates tumor suppressor p53 protein in response to DNA damage through complex formation and acetylation."
06/30/2015 - "Further confirming these results, Runx1 protein levels were found decreased in tumor xenografts upon G-1 treatment. "
01/01/2014 - "RUNX1 expression did not influence outcome of oestrogen receptor (ER)-positive or HER2-positive disease, however on univariate analysis a high RUNX1 protein was significantly associated with poorer cancer-specific survival in patients with ER-negative (P<0.05) and with triple negative (TN) invasive breast cancer (P<0.05). "
01/16/2014 - "Overexpression of transcription factors runt-related transcription factor 1 (RUNX1) and nuclear factor, erythroid-derived 2 (NF-E2) was reported in granulocytes of patients with polycythemia vera and other myeloproliferative neoplasms (MPNs). "
06/01/2013 - "Since its discovery from a translocation in leukemias, the runt-related transcription factor 1/acute myelogenous leukemia-1 (RUNX1/AML1), which is widely expressed in hematopoietic cells, has been extensively studied. "
01/31/2008 - "Leukemia-related abnormal Runx1 fusion protein AML1-ETO, which fuses the N-terminal 177 amino acid residues of the Runx1 protein in frame to ETO (eight-twenty-one) protein, also interacted with HIF-1alpha protein with greater ability than Runx1 itself. "
12/12/2013 - "Heterozygous alterations in FLI1 and RUNX1, encoding Friend leukemia integration 1 and RUNT-related transcription factor 1, respectively, which have a fundamental role in megakaryocytopoeisis, were identified in 6 patients, 4 of whom had mild thrombocytopenia. "
01/01/2014 - "The runt-related transcription factor 1 (RUNX1) gene is a transcription factor that acts as a master regulator of hematopoiesis and represents one of the most frequent targets of chromosomal rearrangements in human leukemias. "
08/01/2012 - "In addition to the aberrantly truncated RUNX1 protein, the DTX2 antisense sequence may play some role in the development of leukemia carrying the t(7;21) translocation."
04/01/2013 - "Sequencing revealed a nonsense c.958C →T RUNX1 mutation both at diagnosis and disease progression, resulting in a p.Arg320X carboxyl-terminal truncated RUNX1 protein. "
03/01/2013 - "Mutations associated with disease progression such as isocitrate dehydrogenase (IDH) 1, IDH2, EZH2, serine/arginine-rich splicing factor 2 (SRSF2), p53, casitas B-lineage lymphoma (c-CBL), ikaros zinc fingers (IKZF), neurofibromin 1 (NF1) and runt-related transcription factor 1 (RUNX1) are described. "
|1.||Transcription Factors (Transcription Factor)
|2.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|3.||Messenger RNA (mRNA)
|4.||COUP Transcription Factor II
|5.||Histone Acetyltransferases (Histone Acetyltransferase)
|6.||GATA2 Transcription Factor
|7.||YY1 Transcription Factor
|8.||NFATC Transcription Factors
|10.||Neurofibromin 1 (Neurofibromin)
|1.||Heterologous Transplantation (Xenotransplantation)