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Core Binding Factor Alpha 2 Subunit

A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. Runx1 is frequently mutated in human LEUKEMIAS.
Also Known As:
AML1A Protein; AML1B Protein; AML1C Protein; AML1D Protein; Acute Myeloid Leukemia 1 Protein; Acute Myeloid Leukemia 1A Protein; Acute Myeloid Leukemia 1B Protein; Acute Myeloid Leukemia 1C Protein; Acute Myeloid Leukemia 1D Protein; Core-Binding Factor Alpha 2 Protein; Pebp2a2 Protein; Runt-Related Transcription Factor 1; Runx1 Protein; Core Binding Factor Alpha 2 Protein; Runt Related Transcription Factor 1
Networked: 34 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Nakagawa, Masahiro: 2 articles (06/2013 - 12/2004)
2. Kurokawa, Mineo: 2 articles (06/2013 - 12/2004)
3. Mitani, Kinuko: 2 articles (08/2012 - 12/2004)
4. Speck, Nancy A: 2 articles (01/2011 - 11/2005)
5. Abonante, Sergio: 1 article (06/2015)
6. Cirillo, Francesca: 1 article (06/2015)
7. Maggiolini, Marcello: 1 article (06/2015)
8. Panno, Maria Luisa: 1 article (06/2015)
9. Pellegrino, Michele: 1 article (06/2015)
10. Vivacqua, Adele: 1 article (06/2015)

Related Diseases

1. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
2. Neoplasms (Cancer)
3. Rheumatoid Arthritis
4. Leukemia
5. Disease Progression

Related Drugs and Biologics

1. Transcription Factors (Transcription Factor)
2. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
3. Messenger RNA (mRNA)
4. COUP Transcription Factor II
5. Histone Acetyltransferases (Histone Acetyltransferase)
6. GATA2 Transcription Factor
7. YY1 Transcription Factor
8. NFATC Transcription Factors
9. Ubiquitin
10. Neurofibromin 1 (Neurofibromin)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)