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Core Binding Factors (Core-Binding Factor)

Heterodimeric transcription factors containing a DNA-binding alpha subunits, (CORE BINDING FACTOR ALPHA SUBUNITS), along with a non-DNA-binding beta subunits, CORE BINDING FACTOR BETA SUBUNIT. Core Binding Factor regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression.
Also Known As:
Core-Binding Factor; PEBP2 Transcription Factor; Polyomavirus Enhancer Binding Protein 2; Binding Factors, Core; Core Binding Factor; Factors, Core Binding; Transcription Factor, PEBP2
Networked: 223 relevant articles (11 outcomes, 13 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Ravandi, Farhad: 9 articles (11/2015 - 12/2008)
2. Beghini, Alessandro: 8 articles (01/2015 - 01/2002)
3. Borthakur, Gautam: 7 articles (11/2015 - 12/2008)
4. Paschka, Peter: 7 articles (01/2013 - 08/2006)
5. Kantarjian, Hagop: 6 articles (10/2014 - 12/2008)
6. Bloomfield, Clara D: 6 articles (04/2010 - 09/2003)
7. Marcucci, Guido: 6 articles (04/2010 - 09/2003)
8. Larizza, Lidia: 6 articles (05/2006 - 01/2002)
9. Preudhomme, Claude: 5 articles (06/2015 - 03/2009)
10. Kim, Hyeoung-Joon: 5 articles (05/2015 - 06/2010)

Related Diseases

1. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
2. Leukemia
3. Anoxia (Hypoxia)
4. Myelodysplastic Syndromes (Myelodysplastic Syndrome)
5. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)

Related Drugs and Biologics

1. Transcription Factors (Transcription Factor)
2. Osteocalcin
3. Oxygen
4. dasatinib (BMS 354825)
5. Cytarabine (Cytosar-U)
6. Granulocyte Colony-Stimulating Factor (G-CSF)
7. fludarabine
8. Phosphotransferases (Kinase)
9. Bone Morphogenetic Protein 7
10. Histidine (L-Histidine)

Related Therapies and Procedures

1. Stem Cell Transplantation
2. Drug Therapy (Chemotherapy)
3. Transplants (Transplant)
4. Hematopoietic Stem Cell Transplantation
5. Transplantation (Transplant Recipients)