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Core Binding Factor Alpha 1 Subunit

A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain and is involved in genetic regulation of skeletal development and CELL DIFFERENTIATION.
Also Known As:
AML3 Transcription Factor; Acute Myeloid Leukemia 3 Protein; CBFA-1 Protein; CBFA1 Protein; CBFalpha Runt Domain Transcription Factor 1; CBFalpha1 Protein; Osf2 Transcription Factor; PEBP2alphaA Protein; Runx2 Protein; SEF1 Protein; SL3-3 Enhancer Factor 1; CBFA 1 Protein; SL3 3 Enhancer Factor 1
Networked: 9 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. van Wijnen, Andre J: 4 articles (04/2013 - 12/2009)
2. Stein, Gary S: 4 articles (04/2013 - 12/2009)
3. Lian, Jane B: 3 articles (02/2013 - 12/2009)
4. Antonelli, Marcelo: 2 articles (04/2013 - 12/2009)
5. Tapia, Julio C: 2 articles (04/2013 - 12/2009)
6. Stein, Janet L: 2 articles (03/2010 - 12/2009)
7. Zhao, Shuying: 1 article (11/2015)
8. Yustein, Jason T: 1 article (11/2015)
9. Shuck, Ryan: 1 article (11/2015)
10. Hicks, M John: 1 article (11/2015)

Related Diseases

1. Anoxia (Hypoxia)
2. Necrosis
3. Neoplasms (Cancer)
4. Osteosarcoma (Osteogenic Sarcoma)
5. Prostatic Neoplasms (Prostate Cancer)

Related Drugs and Biologics

1. Caspase 3 (Caspase-3)
2. Proteasome Endopeptidase Complex (Proteasome)
3. Transforming Growth Factor beta (TGF-beta)
4. Nocodazole
5. Mimosine
6. benzyloxycarbonylleucyl-leucyl-leucine aldehyde

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)