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Core Binding Factor alpha Subunits

A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.
Also Known As:
Acute Myeloid Leukemia Proteins; PEBP2A Transcription Factors; Polyomavirus Enhancer A Binding Protein 2; Polyomavirus Enhancer Binding Protein 2, Alpha Subunit; Runt Domain Factor; Runx Proteins; Transcription Factors, PEBP2A; Core Binding Factor alpha Proteins
Networked: 18 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Ito, Yoshiaki: 2 articles (02/2015 - 03/2013)
2. Chuang, Linda Shyue Huey: 2 articles (02/2015 - 03/2013)
3. Bae, Suk-Chul: 1 article (02/2015)
4. van Wijnen, Andre J: 1 article (10/2014)
5. Lian, Jane B: 1 article (10/2014)
6. Lopez-Camacho, Cesar: 1 article (10/2014)
7. Stein, Janet L: 1 article (10/2014)
8. Stein, Gary S: 1 article (10/2014)
9. Speck, Nancy A: 1 article (05/2014)
10. Bhattacharya, Deepta: 1 article (05/2014)

Related Diseases

1. Neoplasms (Cancer)
2. Autoimmune Diseases (Autoimmune Disease)
3. Genetic Predisposition to Disease (Genetic Predisposition)
4. Psoriasis (Pustulosis Palmaris et Plantaris)
5. Pituitary Neoplasms (Pituitary Adenoma)

Related Drugs and Biologics

1. Galectin 3 (LGALS3)
2. Transcription Factors (Transcription Factor)
3. Transforming Growth Factor beta (TGF-beta)
4. Immunoglobulin E (IgE)
5. Estrogens (Estrogen)