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Mannose-Binding Protein-Associated Serine Proteases (Mannose-Binding Protein-Associated Serine Protease)

Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.
Also Known As:
Mannose-Binding Protein-Associated Serine Protease; MASP Proteases; MASP-Related Protein; MASPs; MBL-Associated Serine Proteases; MBP-Associated Serine Protease; MBP-Associated Serine Protease-Related Protein; Mannan-Binding Lectin Serine Proteases; MASP Related Protein; MBL Associated Serine Proteases; MBP Associated Serine Protease; MBP Associated Serine Protease Related Protein; Mannan Binding Lectin Serine Proteases; Mannose Binding Protein Associated Serine Protease; Proteases, MASP; Protein, MASP-Related; Serine Protease, MBP-Associated; Serine Proteases, MBL-Associated
Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Thiel, S: 2 articles (07/2013 - 02/2012)
2. Gál, Péter: 2 articles (07/2013 - 12/2008)
3. Catarino, Sandra J: 1 article (09/2015)
4. Messias-Reason, Iara: 1 article (09/2015)
5. Boschmann, Stefanie E: 1 article (09/2015)
6. Mendes, Hellen C: 1 article (09/2015)
7. Goeldner, Isabela: 1 article (09/2015)
8. Boldt, Angelica B W: 1 article (09/2015)
9. Beltrame, Marcia H: 1 article (09/2015)
10. Wang, Mian: 1 article (12/2014)

Related Diseases

1. Critical Illness (Critically Ill)
2. Infection
3. Inflammation
4. Hereditary Angioedemas
5. Chronic Hepatitis C

Related Drugs and Biologics

1. Mannose-Binding Protein-Associated Serine Proteases (Mannose-Binding Protein-Associated Serine Protease)
2. Mannose-Binding Lectin (Mannan-Binding Lectin)
3. ficolin
4. Serine Proteases (Serine Protease)
5. Complement System Proteins (Complement)
6. Tobacco Smoke Pollution (Passive Smoking)
7. Peptide Hydrolases (Proteases)