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Mannose-Binding Protein-Associated Serine Proteases (Mannose-Binding Protein-Associated Serine Protease)

Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.
Also Known As:
Mannose-Binding Protein-Associated Serine Protease; MASP Proteases; MASP-Related Protein; MASPs; MBL-Associated Serine Proteases; MBP-Associated Serine Protease; MBP-Associated Serine Protease-Related Protein; Mannan-Binding Lectin Serine Proteases; MASP Related Protein; MBL Associated Serine Proteases; MBP Associated Serine Protease; MBP Associated Serine Protease Related Protein; Mannan Binding Lectin Serine Proteases; Mannose Binding Protein Associated Serine Protease; Proteases, MASP; Protein, MASP-Related; Serine Protease, MBP-Associated; Serine Proteases, MBL-Associated; MASP
Networked: 78 relevant articles (3 outcomes, 12 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Fujita, Teizo: 9 articles (01/2018 - 06/2007)
2. Takahashi, Minoru: 9 articles (01/2018 - 11/2010)
3. Thiel, Steffen: 5 articles (01/2020 - 03/2005)
4. Banda, Nirmal K: 5 articles (01/2017 - 11/2010)
5. Gál, Péter: 4 articles (10/2019 - 12/2008)
6. Sekine, Hideharu: 4 articles (01/2018 - 06/2013)
7. Holers, V Michael: 4 articles (01/2017 - 11/2010)
8. Stahl, Gregory L: 4 articles (06/2013 - 11/2010)
9. Takahashi, Kazue: 4 articles (06/2013 - 11/2010)
10. Dobó, József: 3 articles (10/2019 - 12/2008)

Related Diseases

1. Pancreatitis
2. Intraabdominal Infections
3. COVID-19
4. Prediabetic State (Prediabetes)
5. Type 2 Diabetes Mellitus (MODY)

Related Drugs and Biologics

1. Mannose-Binding Protein-Associated Serine Proteases (Mannose-Binding Protein-Associated Serine Protease)
2. Biomarkers (Surrogate Marker)
3. Adiponectin
4. Apolipoproteins E (ApoE)
5. Apolipoproteins
6. Mannose-Binding Lectin (Mannan-Binding Lectin)
7. Serine Proteases (Serine Protease)
8. Proteins (Proteins, Gene)
9. Ficolins
10. Lectins

Related Therapies and Procedures

1. Kidney Transplantation
2. Therapeutics
3. Glycemic Control
4. Medication Errors (Medication Error)
5. Lasers (Laser)