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Complement C3-C5 Convertases (C3 Convertase)

Serine proteases that cleave COMPLEMENT C3 into COMPLEMENT C3A and COMPLEMENT C3B, or cleave COMPLEMENT C5 into COMPLEMENT C5A and COMPLEMENT C5B. These include the different forms of C3/C5 convertases in the classical and the alternative pathways of COMPLEMENT ACTIVATION. Both cleavages take place at the C-terminal of an ARGININE residue.
Also Known As:
C3 Convertase; C5 Convertase; C3 C5 Convertase; C 3 Convertase; C3 Activator; C3-C5 Convertase; C5 Cleaving Enzyme; Complement 3 Convertase; Complement 5 Convertase; Complement C3 Convertases; Complement C5 Convertases; Activator, C3; C3 Convertases, Complement; C3-C5 Convertases, Complement; C5 Convertases, Complement; Complement C3 C5 Convertases; Convertase, C 3; Convertase, C3; Convertase, C3-C5; Convertase, Complement 3; Convertases, Complement C3; Convertases, Complement C3-C5; Convertases, Complement C5
Networked: 66 relevant articles (0 outcomes, 7 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Holers, V Michael: 4 articles (01/2014 - 08/2003)
2. Morgan, B Paul: 3 articles (05/2014 - 01/2011)
3. Stahel, Philip F: 3 articles (01/2014 - 06/2006)
4. Lutz, Hans U: 3 articles (01/2012 - 01/2004)
5. Harris, Claire L: 2 articles (05/2014 - 01/2011)
6. Llorca, Oscar: 2 articles (05/2014 - 01/2011)
7. Taylor, Ronald P: 2 articles (05/2014 - 03/2010)
8. Lindorfer, Margaret A: 2 articles (05/2014 - 03/2010)
9. Weckbach, Sebastian: 2 articles (01/2014 - 07/2012)
10. Tomlinson, Stephen: 2 articles (11/2012 - 07/2012)

Related Diseases

1. Hemolysis
2. Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II)
3. Nephritis
4. Lipodystrophy
5. Infection

Related Drugs and Biologics

1. Complement System Proteins (Complement)
2. Complement C3-C5 Convertases (C3 Convertase)
3. nafamostat
4. Complement Membrane Attack Complex (Membrane Attack Complex)
5. Antigen-Antibody Complex (Immune Complex)
6. Immunoglobulin G (IgG)
7. CD55 Antigens (Decay Accelerating Factor)
8. Properdin
9. Membrane Proteins (Integral Membrane Proteins)
10. Immunoglobulin A (IgA)