An enzyme that catalyzes the oxidation of (R)-2,3-dihydroxy-3-methylbutanoate to (S)-2-hydroxy-2-methyl-3-oxobutanoate in the presence of NADP. It is involved in the biosynthesis of VALINE; LEUCINE; ISOLEUCINE; pentothenate and COENZYME A. This enzyme was formerly classified as EC 188.8.131.52.
Also Known As:
Acetohydroxy Acid Isomeroreductase; Alpha-Acetohydroxyacid Isomeroreductase; Dihydroxyisovalerate Dehydrogenase (Isomerizing); Hydroxyacid Reductoisomerase; Isomeroreductase; Acid Isomeroreductase, Acetohydroxy; Alpha Acetohydroxyacid Isomeroreductase; Isomeroreductase, Acetohydroxy Acid; Isomeroreductase, Alpha-Acetohydroxyacid; Ketol Acid Reductoisomerase; Reductoisomerase, Hydroxyacid; Reductoisomerase, Ketol-Acid
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