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Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)

Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of serotonergic neurons. They are different than SEROTONIN RECEPTORS, which signal cellular responses to SEROTONIN. They remove SEROTONIN from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. Regulates signal amplitude and duration at serotonergic synapses and is the site of action of the SEROTONIN UPTAKE INHIBITORS.
Also Known As:
Serotonin Transporter; Transporter, Serotonin; 5-Hydroxytryptamine Plasma Membrane Transport Protein; 5HT Transporter; Platelet Serotonin Transporter; SERT Proteins; Serotonectin; Serotonin Transporter, Platelets; Sodium-Dependent Serotonin Transporter; 5 Hydroxytryptamine Plasma Membrane Transport Protein; Neurotransmitter Transport Proteins, Serotonin Specific; Neurotransmitter Transporters, Serotonin Specific; Platelets Serotonin Transporter; Serotonin Transporter, Platelet; Serotonin Transporter, Sodium-Dependent; Serotonin-Specific Neurotransmitter Transporters; Sodium Dependent Serotonin Transporter; Transporter, Platelet Serotonin; Transporter, Platelets Serotonin; Transporter, Sodium-Dependent Serotonin; Transporters, Serotonin-Specific Neurotransmitter; Neurotransmitter Transport Proteins, Serotonin-Specific; Neurotransmitter Transporters, Serotonin-Specific; Serotonin Plasma Membrane Transporter Proteins
Networked: 1187 relevant articles (21 outcomes, 253 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Serretti, Alessandro: 17 articles (02/2016 - 05/2002)
2. Golimbet, V E: 15 articles (01/2014 - 12/2000)
3. Goldman, David: 14 articles (06/2014 - 01/2002)
4. Lesch, Klaus-Peter: 12 articles (01/2013 - 01/2003)
5. Cook, Edwin H: 10 articles (08/2015 - 03/2002)
6. Adnot, Serge: 10 articles (02/2015 - 03/2002)
7. Murphy, Dennis L: 10 articles (08/2013 - 01/2003)
8. Gelernter, Joel: 10 articles (05/2013 - 09/2002)
9. Kaleda, V G: 10 articles (03/2008 - 12/2000)
10. Mann, J John: 9 articles (01/2016 - 11/2004)

Related Diseases

1. Major Depressive Disorder (Major Depressive Disorders)
2. Autistic Disorder (Autism)
3. Anxiety Disorders (Anxiety Disorder)
4. Mood Disorders (Mood Disorder)
5. Schizophrenia (Dementia Praecox)

Related Drugs and Biologics

1. Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)
2. Serotonin (5 Hydroxytryptamine)
3. Lithium
4. Fluoxetine (Prozac)
5. Citalopram (Escitalopram)
6. 5-HT2A Serotonin Receptor (5 HT2A Receptor)
7. 3- amino- 4- (2- dimethylaminomethylphenylsulfanyl)benzonitrile
8. Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)
9. Antidepressive Agents (Antidepressants)
10. Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)

Related Therapies and Procedures

1. Tissue Transplantation
2. Drug Therapy (Chemotherapy)
3. Psychophysiology (Physiological Psychology)
4. Phototherapy (Light Therapy)
5. Laparotomy