Adamantinoma

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52 relevant articles (2 outcomes, 5 trials/studies) found for this Disease

Description: A locally aggressive, osteolytic neoplasm of the long bones, probably of epithelial origin and most often involving the TIBIA.

Also Known As:

Adamantinomas

Relationship Network

Disease Context: Research Results

Musculoskeletal Diseases: 83

Bone Diseases: 2376

Bone Neoplasms: 230

Adamantinoma: 52

Related Diseases

1.	Odontoma
2.	Neoplasms (Cancer)
3.	Neoplasm Metastasis (Metastasis)
4.	Ewing's Sarcoma (Sarcoma, Ewing)
5.	Cysts
16 Diseases and 23 more articles analyzed in the Research Interface, order at left...

Experts

1.	Gosheger, Georg: 1 article (04/2008)
2.	Ahrens, Helmut: 1 article (04/2008)
3.	Winkelmann, Winfried: 1 article (04/2008)
4.	Hardes, Jendrik: 1 article (04/2008)
5.	Frey, Sönke P: 1 article (04/2008)
6.	Mii, Yoshio: 1 article (11/2006)
7.	Kasai, Takahiko: 1 article (11/2006)
8.	Fujii, Hiromasa: 1 article (11/2006)
9.	Nonomura, Akitaka: 1 article (11/2006)
10.	Morishita, Toru: 1 article (11/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Adamantinoma:

1.	Trichloroacetic AcidIBA 05/01/1950 - "Case of a grave form of recurrent adamantinoma of the mandible treated by trichloroacetic acid and, at present, clinically and radiologically cured.]" Get all the results and reference details, order at left...
2.	tebufenozide (Mimic)IBA 01/01/2004 - "This study confirmed the epithelial nature of long bone classical and differentiated adamantinomas irrespective of their wide-ranging morphologic pattern that can mimic tumours of various origins" 12/01/1989 - "This study confirmed the epithelial nature of long bone adamantinomas irrespective of their wide-ranging morphologic patterns that can mimic tumors of various origin" Get all the results and reference details, order at left...
3.	DNA (Deoxyribonucleic Acid)IBA 12/01/1995 - "In this study the nature of the mesenchymal and epithelial components of adamantinoma was investigated by DNA flow cytometry, DNA image cytometry, p53 immunohistochemistry, and polymerase chain reaction-based loss of heterozygosity detection at the p53 locus" 12/01/1995 - "DNA aberrations in the epithelial cell component of adamantinoma of long bones." 01/01/1989 - "The DNA content and the nuclear dry mass of 18 keratinized squamous cell carcinomas and their metastases, of one adamantinoma recurrence and two adenoid cystic carcinomas of the oral cavity were determined in comparison to the normal buccal mucosa using Feulgen scanning cytophotometry and interference microscopy" Get all the results and reference details, order at left...
4.	Keratins (Keratin)IBA 06/30/2007 - "After the initial pathology slides of the 13 patients were reviewed with immunohistochemical cytokeratin staining, one patient diagnosis was changed from osteofibrous dysplasia to osteofibrous dysplasia-like adamantinoma" 05/01/2006 - "The primary lesion was retrospectively diagnosed as OFD-like adamantinoma because of presence of keratin-positive epithelial cells within the stroma" 12/01/2003 - "These dedifferentiated areas showed pankeratin positivity as well, although there were some changes in keratin subclass profile compared with other classic adamantinomas" 07/01/1998 - "The lesion had abundant epithelial component with formation of keratin pearls, a pattern that has been described only in classic adamantinoma occurring in adults" 10/01/1994 - "Two patients who had had a presumed osteofibrous dysplasia-like adamantinoma, which contained few isolated keratin-positive epithelial cells within the stroma at the time of presentation, had a full-blown adamantinoma at the time of the local recurrence" Get all the results and reference details, order at left...
5.	VimentinIBA 01/01/2004 - "Both types of adamantinoma were positive for cytokeratins in coexpression with vimentin" 03/01/1995 - "All adamantinomas were positive for cytokeratins often in coexpression with vimentin, at least focally" 07/01/1994 - "In 71% of adamantinomas, vimentin showed strong immunoreactivity in the tumour cells of nests and tubules" 08/01/2004 - "The correct histological diagnosis of differentiated adamantinoma depends on factors such as the uniform predominance of an osteofibrous dysplasia-like pattern, and scattered epithelial elements positive for cytokeratin and vimentin" 01/01/1992 - "Excluding two cases of Ewing-like adamantinoma, the other three cases of adamantinoma were also positive for cytokeratin and vimentin" Get all the results and reference details, order at left...
6.	CollagenIBA 02/01/1997 - "Collagens I and III, and fibronectin were generally present in the (osteo-)fibrous tissue of adamantinoma but lacked in the epithelial aggregates" 01/01/2004 - "Staining for collagen IV, laminin and galectin-3, a laminin binding protein was seen in OFD and around cell nests in adamantinoma" Get all the results and reference details, order at left...
7.	AntibodiesIBA 07/01/1994 - "CKAE1/AE3 and CK19 were strongly expressed in all morphological patterns of adamantinoma emphasizing their epithelial origin, while the antibodies to CK8 and CK18 showed a high percentage of negative responses" 02/01/1999 - "Two of the three cases were originally described as adamantinomas or nontypical Ewing's sarcoma before the availability of genetic characterization.) In addition, traditional cytogenetic analysis and a unique combined interphase molecular cytogenetic/ immunocytochemical approach with bicolor 11;22 translocation breakpoint flanking probes (cosmids) and pancytokeratin antibodies were performed on one neoplasm" Get all the results and reference details, order at left...
8.	OsteopontinIBA 01/01/2004 - "Osteonectin was detected in both the epithelial and fibrous components of adamantinomas, but osteopontin and osteocalcin were not seen in classical adamantinomas" Get all the results and reference details, order at left...
9.	Galectin 3 (LGALS3)IBA 01/01/2004 - "Staining for collagen IV, laminin and galectin-3, a laminin binding protein was seen in OFD and around cell nests in adamantinoma" Get all the results and reference details, order at left...
10.	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/01/1998 - "Expression of growth factors and their receptors in adamantinoma of long bones and the implication for its histogenesis." Get all the results and reference details, order at left...
38 Drugs and Important Bio-Agents and 34 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	X-Ray Therapy 04/15/1977 - "X-ray therapy was used on 14 selected adamantinomas and 2 ameloblastic odontomas, with beneficial results" Get all the results and reference details, order at left...
2.	Replantation 10/01/1977 - "Clinical and histological studies on methods for reimplantation of the mandible after resection for adamantinoma or other benign tumors]" 07/01/1999 - "In 6 patients with primary malignant bone tumors (4 Ewing, 1 recurrent Adamantinoma, 1 maligne Haemangioperizytoma) the local therapy was performed as intraoperative extracorporeal irradiation and replantation" 11/01/2003 - "In 13 patients with primary malignant bone tumors (10 Ewing's sarcoma, 1 parosteal osteosarcoma, 1 adamantinoma recurrence, and 1 MFH) local therapy was performed as intraoperative extracorporeal irradiation and replantation (IEIR) of the involved bone segment (5 tibia, 2 femur, and 6 pelvis)" Get all the results and reference details, order at left...
3.	Limb Salvage 08/01/2000 - "The purpose of this study was to evaluate the characteristics of adamantinoma of long bones as well as the oncological outcome and the complications of limb salvage operations" 08/01/2000 - "METHODS: A retrospective study was designed to evaluate the clinical outcomes of limb salvage operations for the treatment of adamantinoma" 08/01/2000 - "Limb salvage is currently the treatment of choice for most adamantinomas" 08/01/2000 - "CONCLUSIONS: Current treatment of adamantinoma, including en bloc tumor resection with wide operative margins and limb salvage, provides lower rates of local recurrence than has been previously reported" Get all the results and reference details, order at left...
4.	Transplants (Transplant) 02/28/1970 - "Immediate reconstruction with bone grafts using the intra-oral route, after mandibular resection for adamantinoma]" 08/08/1963 - "BRIEF REPORT ABOUT THE USE OF A BONE TRANSPLANT IN RESECTION OF THE MANDIBLE FOR ADAMANTINOMA" 10/01/1950 - "Distant results of an immediate bone graft and autogenous condylar graft in a case of adamantinoma of the mandible." 09/01/1980 - "Follow-up of 5 cases of mandibular adamantinoma treated by osteotomy and mixed grafts]" 09/01/1980 - "The examination after fifteen years of five cases of mandibular adamantinoma treated with an operation performed in two stages (graft of metallic prosthesis and osseous autograft) has confirmed the success of this surgical method" Get all the results and reference details, order at left...
5.	Curettage 03/01/2008 - "Of the 11 OFD patients with follow-up (median, 4.5 y), all 3 who underwent incisional biopsy had persistent, nonprogressive disease and 2 of 8 who underwent curettage or wide excision had recurrence; none developed adamantinoma" 11/01/1992 - "Subsequent curettage of the specimen revealed an adamantinoma with a prominent fibrous component" 03/01/2006 - "A 26-year-old female with a tibial lesion diagnosed as an adamantinoma was treated with intra-lesional curettage, bone grafting and intra-medullary nailing" 05/01/1988 - "Small benign lesions occurring in the mandible, such as dental cysts or adamantinoma, are treated adequately by the dental surgeon using an intraoral approach and curettage (Brånemark et al., 1975)" Get all the results and reference details, order at left...
13 Therapies and Procedures and 20 more articles analyzed in the Research Interface, order at left...

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