|1.||Baker, James R: 39 articles (12/2015 - 09/2002)|
|2.||Shi, Xiangyang: 31 articles (10/2015 - 07/2005)|
|3.||Bryszewska, Maria: 22 articles (11/2015 - 01/2006)|
|4.||Shen, Mingwu: 20 articles (10/2015 - 07/2009)|
|5.||Kannan, Rangaramanujam M: 18 articles (09/2015 - 01/2004)|
|6.||Thomas, Thommey P: 18 articles (08/2015 - 06/2004)|
|7.||Kotlyar, Alina: 16 articles (08/2015 - 06/2004)|
|8.||Klajnert, Barbara: 15 articles (03/2014 - 01/2006)|
|9.||Majoral, Jean-Pierre: 12 articles (11/2015 - 06/2004)|
|10.||Mishra, Manoj K: 12 articles (09/2015 - 11/2010)|
12/28/2013 - "This review analyzes these techniques applied to liposomal, PEI, dendrimer, stem cell and viral gene delivery systems in order to determine the techniques that are most effective in achieving tumor specific gene expression after systemic administration. "
04/04/2011 - "In contrast the equivalent dendrimer comprising uncapped MTX conjugated to the dendrimer via the same hexapeptide linker did not reduce tumor growth, presumably reflecting very rapid clearance of the construct. "
09/14/2004 - "In cell culture, ODN-dendrimer conjugates were effective in inhibiting cancer cell growth that correlated with a marked knockdown in EGFR protein expression. "
12/03/2014 - "A "cluster-bomb"-like lipid-dendrimer nanoassembly synergizes the functions of its components and thereby efficiently accomplishes the drug delivery cascade for high efficacy in treating cancer. "
01/01/2013 - "A significantly enhanced oncolytic effect was observed following systemic application of dendrimer-coated adenovirus that was further increased by additional treatment with a therapeutic dose of (131)I. These results demonstrate restricted virus tropism and tumor-selective retargeting after systemic application of coated, EGFR-targeted adenoviruses therefore representing a promising strategy for improved systemic adenoviral NIS gene therapy.Molecular"
08/01/2002 - "Dendrimers are macromolecules with broad-spectrum antiviral activity and minimal toxicity effective in animal models in preventing transmission of herpes simplex virus (HSV) infection. "
02/04/2013 - "Taken together, this study clearly proves noncovalent, charge-based coating of Ad vectors with ligand-equipped dendrimers as a viable strategy for efficient transduction of cells otherwise refractory to Ad infection."
12/01/2011 - "We report in this study that the dendrimer-dsiRNA treatment suppressed HIV-1 infection by several orders of magnitude and protected against viral induced CD4(+) T-cell depletion. "
11/13/2015 - "Our results suggest that membranolytic dendrimer 14, targeting cellular apoptotic pathway and impairing the cell wall formation in mature biofilm, may be a potential multifunctional antifungal lead compound for the control of C. albicans infections."
10/01/2015 - "Our results have clearly demonstrated that these dendrimers have high potency as a topical microbicide against HIV-1 infection."
03/01/2009 - "When the formulation was administered at 48-h intervals, the efficacy of LMWH encapsulated in pegylated dendrimers in reducing thrombus weight in a rodent model was very similar to that of subcutaneous LMWH administered at 24-h intervals. "
01/01/2015 - "Collectively, this review focuses on detailed note on the delivery and improved solubility of poorly soluble anti-cardiovascular bioactives, nitric oxide (NO) donor for anti-thrombosis, gene delivery and delivery of receptor agonists for cardio-protective action of the receptors using dendrimers. "
09/02/2010 - "Formulations containing generation 5 (G5) PAMAM dendrimers with a heparin/G5 molar ratio of 0.5-1.2 are proposed as effective ones for the treatment of thrombosis in noninvasive delivery routes such as nasal, pulmonary, transdermal, and oral routes. "
11/20/2014 - "Previously reported polyP inhibitors based on polycationic substances, such as polyethylenimine, polyamidoamine dendrimers, and polymyxin B, although they attenuate thrombosis, all have significant toxicity in vivo, likely due to the presence of multiple primary amines responsible for their polyP binding ability. "
08/01/2014 - "In this study, we reported that PAMAM dendrimers induced both cytotoxicity and autophagic flux in a panel of human glioma cell lines. "
12/28/2013 - "We comprehensively studied the cellular uptake behavior of these dendrimers, into glioma C6 cell line, under the influence of various endocytosis inhibitors. "
11/01/2009 - "Here, we present the synthesis, characterization, and cellular internalization into C6 rat glioma cells of a TSPO targeted dendrimer imaging agent."
01/01/2009 - "The BTB of both ectopic RG-2 gliomas and orthotopic RG-2 gliomas was not permeable to Gd-G8 dendrimers. "
01/01/2008 - "Of the permeable functionalized dendrimer generations, those that possessed long blood half-lives could accumulate within glioma cells. "
|5.||Breast Neoplasms (Breast Cancer)
08/01/2014 - "Thus, the mPEGylated peptide dendrimer-DOX conjugate-based nanoparticle may be a potential nanoscale drug delivery vehicle for the breast cancer therapy. "
11/01/2013 - "The cytotoxicity of the prepared dendrimers was tested against MCF-7 breast cancer cells. "
05/01/2013 - "The in vivo experiments were carried out in mice xerograft breast cancer models, the results indicated that the inhibition efficiency of the DOX-dendrimer conjugates was much better than that of free DOX·HCl."
05/01/2013 - "The drug-dendrimer conjugates could be internalized in mice breast cancer 4T1 cells efficiently. "
01/01/2013 - "Multifunctional dendrimer-based nanoparticles for in vivo MR/CT dual-modal molecular imaging of breast cancer."
|1.||Folic Acid (Vitamin M)
|7.||Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)
|10.||Small Interfering RNA (siRNA)
|1.||Drug Therapy (Chemotherapy)
|2.||Heterologous Transplantation (Xenotransplantation)
|4.||Photochemotherapy (Photodynamic Therapy)