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G(M2) Activator Protein

An essential cofactor for the degradation of G(M2)GANGLIOSIDE by lysosomal BETA-N-ACETYLHEXOSAMINIDASES. Genetic mutations resulting in loss of G(M2) activator protein are one of the causes of TAY-SACHS DISEASE, AB VARIANT.
Also Known As:
GM(2) Activating Protein; GM2 Activator Protein; Hexosaminidase Activator; Activator Protein, GM2
Networked: 21 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Yuan, Weiming: 1 article (07/2015)
2. Huang, Longguang: 1 article (07/2015)
3. Tang, Juan: 1 article (07/2015)
4. Rong, Xiao: 1 article (07/2015)
5. Zhou, Wei: 1 article (07/2015)
6. Wang, Ping: 1 article (07/2015)
7. Minnich, Sara: 1 article (01/2014)
8. Teigen, Claire: 1 article (01/2014)
9. Raymond, Kimiyo: 1 article (01/2014)
10. Hall, Patricia: 1 article (01/2014)

Related Diseases

1. Necrotizing Enterocolitis
2. GM2 Gangliosidoses (GM2 Gangliosidosis)
3. Tay-Sachs Disease
4. Sandhoff Disease (Sandhoff's Disease)
5. Atherosclerosis

Related Drugs and Biologics

1. G(M2) Ganglioside (Ganglioside GM2)
2. Hexosaminidase A (Hex A)
3. Complementary DNA (cDNA)
4. Taurocholic Acid (Sodium Taurocholate)
5. Hexosaminidases (Hexosaminidase)
6. Carbon Monoxide
7. beta-N-Acetylhexosaminidases