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MAP Kinase Kinase 4

A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES and the RETINOID X RECEPTORS. It takes part in a SIGNAL TRANSDUCTION pathway that is activated in response to cellular stress.
Also Known As:
JN Kinase Kinase; JNK Kinase; JNK-Activating Protein Kinase; JNKK1 Protein Kinase; Jun Amino-Terminal Kinase Kinase; MEK4 Protein Kinase; Mitogen-Activated Protein Kinase Kinase 4; SAP Kinase Kinase 1; SAP Kinase-Extracellular Signal-Regulated Kinase Kinase 1; SAPK-ERK Kinase 1; SEK1 Protein Kinase; Stress-Activated Protein Kinase Kinase 1; JNK Activating Protein Kinase; Jun Amino Terminal Kinase Kinase; Kinase, JNKK1 Protein; Mitogen Activated Protein Kinase Kinase 4; Protein Kinase, JNK-Activating; Protein Kinase, JNKK1; Protein Kinase, MEK4; Protein Kinase, SEK1; SAP Kinase Extracellular Signal Regulated Kinase Kinase 1; SAPK ERK Kinase 1; Stress Activated Protein Kinase Kinase 1
Networked: 51 relevant articles (0 outcomes, 5 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Rinker-Schaeffer, Carrie W: 6 articles (06/2012 - 11/2002)
2. Clark, Robert: 3 articles (12/2012 - 10/2011)
3. Otto, Kristen: 3 articles (02/2012 - 03/2008)
4. Vander Griend, Donald J: 3 articles (10/2011 - 11/2002)
5. Khan, Shaheena: 2 articles (12/2012 - 10/2011)
6. Rinker-Schaeffer, Carrie: 2 articles (12/2012 - 02/2012)
7. Montag, Anthony: 2 articles (06/2012 - 11/2002)
8. Yamada, S Diane: 2 articles (06/2012 - 11/2002)
9. Macleod, Kay: 2 articles (02/2012 - 04/2008)
10. Lotan, Tamara: 2 articles (02/2012 - 04/2008)

Related Diseases

1. Ovarian Neoplasms (Ovarian Cancer)
2. Squamous Cell Carcinoma (Epidermoid Carcinoma)
3. Reperfusion Injury
4. Sleep Deprivation
5. Burns

Related Drugs and Biologics

1. Phosphotransferases (Kinase)
2. NF-kappa B (NF-kB)
3. Serine (L-Serine)
4. MAP Kinase Kinase Kinase 5
5. JNK Mitogen-Activated Protein Kinases
6. Protein Kinases (Protein Kinase)
7. p38 Mitogen-Activated Protein Kinases
8. Thioredoxins
9. mitogen-activated protein kinase kinase kinase 11
10. Dual Specificity Phosphatase 1

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)