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raf Kinases

A family of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES. They are MAP kinase kinase kinases that play important roles in SIGNAL TRANSDUCTION.
Also Known As:
Proto-Oncogene Proteins raf; raf Proto-Oncogene Proteins; raf Serine-Theonine Protein Kinases; Kinases, mil-raf Protein; Kinases, raf; MIL RAF Proteins; Protein Kinases, mil-raf; Proteins raf, Proto-Oncogene; Proto Oncogene Proteins raf; Proto-Oncogene Proteins, raf; mil raf Protein Kinases; raf Proto Oncogene Proteins; raf Serine Theonine Protein Kinases; MIL-RAF Proteins; mil-raf Protein Kinases; raf MAP Kinase Kinase Kinases
Networked: 41 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Guo, Xiao-Xi: 2 articles (11/2015 - 01/2015)
2. An, Su: 2 articles (11/2015 - 01/2015)
3. Ward, Richard: 2 articles (11/2015 - 01/2015)
4. Liu, Ying: 2 articles (11/2015 - 01/2015)
5. Xu, Tian-Rui: 2 articles (11/2015 - 01/2015)
6. Yang, Yang: 2 articles (11/2015 - 01/2015)
7. Rosen, Neal: 2 articles (04/2014 - 12/2008)
8. Solit, David B: 2 articles (04/2014 - 12/2008)
9. Chapman, Paul B: 2 articles (04/2014 - 12/2008)
10. Kolch, Walter: 2 articles (04/2013 - 04/2004)

Related Diseases

1. Melanoma (Melanoma, Malignant)
2. Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
3. Portal Hypertension
4. Neoplasms (Cancer)
5. Hepatocellular Carcinoma (Hepatoma)

Related Drugs and Biologics

1. sorafenib (BAY 43-9006)
2. Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)
3. Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)
4. Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)
5. Phosphotransferases (Kinase)
6. Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
7. Protein Kinases (Protein Kinase)
8. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
9. ral Guanine Nucleotide Exchange Factor
10. GTP Phosphohydrolases (GTPases)

Related Therapies and Procedures

1. Ligation
2. Heterologous Transplantation (Xenotransplantation)