|1.||Grant, Steven: 5 articles (11/2009 - 02/2005)|
|2.||Dent, Paul: 5 articles (11/2009 - 02/2005)|
|3.||Wang, Kai: 4 articles (12/2015 - 01/2008)|
|4.||Wu, Wei: 4 articles (01/2014 - 12/2008)|
|5.||Elizalde, Patricia V: 4 articles (04/2013 - 01/2004)|
|6.||Proietti, Cecilia J: 4 articles (04/2013 - 01/2004)|
|7.||Schillaci, Roxana: 4 articles (04/2013 - 01/2004)|
|8.||Altavilla, Domenica: 4 articles (02/2009 - 10/2004)|
|9.||Minutoli, Letteria: 4 articles (02/2009 - 10/2004)|
|10.||Bitto, Alessandra: 4 articles (02/2009 - 10/2004)|
01/15/2015 - "Although many signaling pathways could influence chemoresistance of tumor cells, the extracellular signal-regulated kinase 1 and 2 (ERK1/2) pathway has gained significant attention because of its implications in signaling and which has crosstalk with other signaling pathways. "
07/01/2014 - "Stable knockdown of OVA66 in cancer cells attenuated phosphorylation of IGF-1R and extracellular signal-regulated kinase 1/2 (ERK1/2)-Hsp27; similarly, a higher level of p-IGF-1R and ERK1/2-Hsp27 signaling was also detected after OVA66 overexpression in HO8910 cells. "
01/01/2014 - "In addition, the mAb(P) CO17-1A × BR55 significantly inhibited the extracellular signal-regulated kinase 1 and 2 (ERK1/2) phosphorylation in cancer cells and tumors. "
01/01/2014 - "Here, we investigated API5 expression in cervical cancer, its clinical significance, and its relationship with phosphorylated extracellular signal-regulated kinase 1 and 2 (pERK1/2) in development and progression of cervical cancer. "
01/01/2011 - "This effect was particularly pronounced in the AG1478-treated tumor cells and was associated with the level of extracellular-signal regulated kinase-1/2 phosphorylation which appeared more efficiently inhibited in the cell lines exhibiting the K497 EGFR polymorphism. "
10/01/2002 - "In conclusion, we believe that the p42/p44 MAPK-dependent signaling pathway represents an important survival mechanism against reperfusion injury."
10/01/2002 - "We hypothesized that activation of potential survival pathways such as p42/p44 MAPK may prevent lethal reperfusion injury. "
12/01/2001 - "We therefore examined the effects of transforming growth factor-beta1 (TGF-beta1) on reperfusion injury and assessed the role of p42/p44 MAPK signaling in TGF-beta1-induced protection. "
10/01/2015 - "Heme oxygenase-1 ameliorates kidney ischemia-reperfusion injury in mice through extracellular signal-regulated kinase 1/2-enhanced tubular epithelium proliferation."
02/14/2009 - "Mitogen-activated protein kinase 3/mitogen-activated protein kinase 1 activates apoptosis during testicular ischemia-reperfusion injury in a nuclear factor-kappaB-independent manner."
12/01/2014 - "Furthermore, we observed that while Akt phosphorylation was enhanced in both immature and mature DC exposed to hypoxia, other signaling pathways, such as p38 and p42/p44 MAPK, were differently affected during hypoxic treatment. "
04/01/2013 - "Western blotting results showed that DT-13 suppressed the increased level of hypoxia-inducible factor 1α, p-extracellular signal-regulated kinase 1/2 and p-Akt induced by hypoxia. "
11/01/2012 - "Collectively, we demonstrated for the first time that ROS and extracellular signal-regulated kinase 1/2 (ERK1/2)-mediated reduction of GLT-1 expression may be involved in chemical hypoxia-induced neural injury and that H2S attenuates this injury partly by upregulating GLT-1 expression in PC12 cells."
05/01/2012 - "Further, we used loss- and gain-function approaches to elucidate the underlying mechanism and found that TGF-β1 induced GPx-1 through activation of the TGF-β receptor type I (TGF-βRI)/Smad2/extracellular-signal-regulated kinase 1/2 (ERK1/2)/hypoxia-inducible factor-1α (HIF-1α) signaling pathway. "
10/01/2006 - "We have reported that 15-hydroxyeicosatetraenoic acid (15-HETE) induces pulmonary artery (PA) contraction in rats exposed to hypoxia by activating extracellular signal-regulated kinase 1/2 (ERK1/2). "
12/01/2006 - "The current study was undertaken to investigate the time course of gastric ischemia-reperfusion (GI-R)-induced gastric mucosal injury and repair and whether extracellular signal-regulated kinase 1/2 (ERK1/2) were involved in GI-R-induced gastric mucosal injury and repair. "
02/01/2012 - "Extracellular signal-regulated kinase 1/2 activation is involved in intermedin1-53 attenuating myocardial oxidative stress injury induced by ischemia/reperfusion."
12/01/2006 - "Extracellular signal-regulated kinase 1- and 2-mediated gastric mucosal injury and repair in gastric ischemia-reperfusion of rats."
08/01/2009 - "To explore the change tendency of hypoxia-inducible factor-1alpha (HIF-1alpha) and extracellular signal-regulated kinase 1/2 (ERK1/2) in fetal rat cerebral cortex neurons cultured in vitro after hypoxia-ischemia reperfusion and to investigate their mutual relationship. "
09/20/2004 - "A role for some MAPKs (e.g., extracellular signal-regulated kinase, Erk1/2) has been documented in response to certain physiological stimuli, such as ischemia, visceral pain and electroconvulsive shock. "
10/15/2011 - "Extracellular signal-regulated kinase 1/2 (ERK1/2) signalling is a key pathway in cardiomyocyte hypertrophy and survival in response to many different stress stimuli. "
01/01/2005 - "Stretch-induced hypertrophy required cell cycle entry, and was prevented by specifically blocking extracellular signal-regulated kinase 1/2 (Erk1/2) or Akt. "
12/01/2010 - "It also increased cardiomyocytes hypertrophy, expression of atrial natriuretic peptide, and significantly activated the extracellular signal-regulated kinase 1/2 (ERK1/2) and the phosphatidylinositol-3-kinase (PI3-K)/protein kinase B (Akt) signaling pathways in cardiomyocytes. "
01/01/2010 - "Extracellular signal-regulated kinase 1/2 inhibition in vivo (U0126) prevented hypertrophy in high-flow arteries. "
02/01/2007 - "The inhibition of proliferation and stimulation of hypertrophy induced by Ang II involves both p42/p44(mapk) and p38 MAPK activation. "
|2.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|3.||Protein Kinases (Protein Kinase)
|4.||U 0126 (UO 126)
|5.||Protein Kinase C
|6.||Epidermal Growth Factor Receptor (EGF Receptor)
|7.||Proteins (Proteins, Gene)
|8.||JNK Mitogen-Activated Protein Kinases
|9.||Transcription Factors (Transcription Factor)
|10.||Calcium-Calmodulin-Dependent Protein Kinases
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)