|1.||Chang, Long-Sen: 13 articles (01/2016 - 07/2008)|
|2.||Higgins, Linda S: 12 articles (01/2010 - 02/2002)|
|3.||Kozawa, Osamu: 11 articles (06/2012 - 06/2005)|
|4.||Willette, Robert N: 10 articles (01/2013 - 04/2002)|
|5.||Noguchi, Koichi: 9 articles (02/2015 - 04/2004)|
|6.||Kipling, David: 9 articles (10/2013 - 09/2007)|
|7.||Davis, Terence: 9 articles (10/2013 - 09/2007)|
|8.||Protter, Andrew A: 9 articles (01/2010 - 06/2003)|
|9.||Medicherla, Satyanarayana: 9 articles (01/2010 - 08/2006)|
|10.||Chaudry, Irshad H: 9 articles (04/2009 - 07/2003)|
04/01/2013 - "These results taken together with earlier studies on systemic administration of p38 MAPK inhibitors in rodents and humans suggest that direct intrapulmonary delivery of a p38 MAPK inhibitor is less effective in inhibiting inflammation and is associated with unexpected procoagulant effects in the bronchoalveolar space."
05/11/2011 - "Efficacy of NP202 was also associated with reduced p38 MAPK activation, inflammation and apoptotic cell death."
08/01/2013 - "In conclusion, our study provides novel data demonstrating that the p38 MAPK/NF-κB pathway is important in the induction of DOX-induced inflammation and cytotoxicity in H9c2 cardiac myocytes."
01/01/2013 - "The present study has demonstrated the new mechanistic evidence that exogenous H2S attenuates the DOX-induced inflammation and cytotoxicity by inhibiting p38 MAPK/NF-κB pathway in H9c2 cardiac cells. "
01/01/2013 - "The present study attempts to test the hypothesis that exogenous H2S might protect cardiomyocytes against the DOX-induced inflammation and cytotoxicity through inhibiting p38 MAPK/NF-κB pathway. "
08/15/2015 - "The altered phenotype of TAMs in apn(-/-) mice was associated with a marked decrease in phospho-p38 and treatment with a p38 MAPK inhibitor significantly reduced tumor size and increased MHC II expression on TAMs in WT mice, implying p38 MAPK signaling pathway may contribute to APN-mediated TAM polarization. "
04/12/2007 - "This tumor-prone phenotype of Wip1 is fully eliminated through attenuation of proliferation by activating the MKK6/p38 mitogen-activated protein kinases (MAPK) cascade in mice bearing a constitutively active form of MKK6. "
04/20/2015 - "Studies in mouse models have shown that the p38 MAPK pathway regulates homeostasis in colon epithelial cells but also plays an important role in colon tumor maintenance. "
08/01/2013 - "In this study, we analysed p38 MAPK isoform expression in oesophageal cancer cell lines as well as human normal and tumour tissue. "
01/01/2011 - "These studies illustrate that forced expression of Brk/PTK6 in non-transformed mammary epithelial cells mediates p38 MAPK phosphorylation and promotes increased cellular survival, delayed involution, and latent tumor formation. "
02/01/2008 - "Mechanisms of the joint-protective effects of p38 MAPK inhibitors in rodent arthritis."
09/13/2012 - "This compound represents a highly potent inhibitor of p38 MAP kinase with regard to in vivo activity in an adjuvant-induced arthritis model."
02/09/2012 - "Inhibition of MK2 has been shown to offer advantages over that of p38 MAPK in the development of cures for inflammatory diseases such as arthritis. "
02/01/2006 - "Both p38 MAPK inhibitors significantly reduced clinical signs of TNF-mediated arthritis. "
11/01/2010 - "Consequently, p38 MAPK inhibitors have attracted considerable interest as potential treatments of rheumatoid arthritis (RA), and studies in murine models of arthritis have yielded promising results. "
04/01/2012 - "Inhibition of the p38 MAPK pathway ameliorates renal fibrosis in an NPHP2 mouse model."
02/01/2011 - "Long-term administration of Scu improved the cardiac function of MI rats by inhibiting interstitial fibrosis, and the mechanisms may involve the suppression of pro-fibrotic cytokine TGFβ1 expression and inhibition of p38 MAPK and ERK1/2 phosphorylation."
06/20/2009 - "Recent studies have suggested that p38 mitogen-activated protein kinases (MAPK) signalling pathway plays an important role in hepatic fibrosis. "
06/01/2012 - "We found that disruption of TβRII inhibited severe tubulointerstitial fibrosis in the UUO kidney, which was associated with the impairment of TGF-β/Smad3 signalling, but not with the ERK/p38 MAP kinase pathway. "
04/01/2012 - "Our results suggest that p38 MAPK and ERK signaling pathways independently affect renal fibrosis in inv mutant mice."
03/01/2014 - "In this study, the authors evaluate the efficacy of topical p38 MAPK inhibition on full-thickness scald burns with immediate and delayed treatment. "
09/01/2009 - "We hypothesized that (1) severe burn up-regulates p38 MAPK activation and results in increased intestinal permeability via augmented expression of MLCK, and (2) inhibition of p38 MAPK will prevent the burn-induced increase in MLCK expression, resulting in improved intestinal barrier integrity. "
10/01/2009 - "In this study, we investigated the effects of local activated p38 MAPK inhibition on burn-induced cardiac dysfunction. "
03/01/2009 - "In this study, we tested whether p38 MAPK is involved in the response to first-degree burn of the hind paw. "
09/01/2003 - "These studies showed by more significant activation of p38 MAP kinase in KCs harvested from burn rats than from shams. "
|3.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|5.||p38 Mitogen-Activated Protein Kinases
|6.||Interleukin-6 (Interleukin 6)
|1.||Drug Therapy (Chemotherapy)
|4.||Heart Transplantation (Grafting, Heart)