|1.||Choi, Yongwon: 9 articles (07/2015 - 07/2002)|
|2.||Kumar, Ashok: 5 articles (03/2014 - 12/2010)|
|3.||Darnay, Bryant G: 5 articles (12/2012 - 07/2002)|
|4.||Zhang, Lan: 4 articles (12/2015 - 10/2011)|
|5.||Fang, Jing: 4 articles (10/2015 - 07/2012)|
|6.||Inoue, Jun-Ichiro: 4 articles (10/2015 - 09/2005)|
|7.||Gohda, Jin: 4 articles (10/2015 - 03/2007)|
|8.||Akiyama, Taishin: 4 articles (10/2015 - 03/2007)|
|9.||Starczynowski, Daniel T: 4 articles (10/2015 - 01/2010)|
|10.||Wang, Ling: 4 articles (09/2015 - 04/2009)|
01/01/2015 - "This current study aims to investigate the functions of Traf6 in different AP models in vitro and in vivo, and to identify the possible regulatory mechanism in the progression of inflammation from mild to severe. "
12/01/2015 - "TRAF6 plays a pivotal role in inflammation induced by E. "
11/01/2014 - "NOD2 downregulates colonic inflammation by IRF4-mediated inhibition of K63-linked polyubiquitination of RICK and TRAF6."
10/01/2014 - "These results clearly demonstrate cross-talk between the TLR and JAK/STAT signaling pathways with direct recruitment of STAT1 by TRAF6 and that the direct activation of STAT1 by TLR signaling suggests a crucial role for STAT1 in TLR-induced inflammation. "
06/03/2014 - "And TRAF6 is probably involved in the pathogenesis of bone metabolism imbalance through modulating synovial inflammation in RA."
01/01/2015 - "JEV infection elevated the expression of miR-146a in JaOArS982 strain which caused downregulation of TRAF6, IRAK1, IRAK2, and STAT1 genes. "
12/01/2014 - "Toll-pathway in tiger shrimp (Penaeus monodon) responds to white spot syndrome virus infection: evidence through molecular characterisation and expression profiles of MyD88, TRAF6 and TLR genes."
04/25/2014 - "Upon infection, the ubiquitination of SopB was absolutely blocked by TRAF6 deletion, as shown in Traf6(-/-) mouse embryonic fibroblasts (MEFs) compared with Traf6(+/+) MEFs. "
01/01/2014 - "CHIKV infection induced the expression of cellular miR-146a, which resulted into down-regulation of TRAF6, IRAK1, IRAK2 and increased replication of CHIKV in human synovial fibroblasts. "
10/01/2013 - "DENV infection significantly induced the expression of miR-146a, which facilitated viral replication by targeting TRAF6 and dampening IFN-β production."
08/01/2013 - "In this study, we show that TRAF6 upregulates expression of hypoxia-inducible factor (HIF)-1α. "
10/01/2013 - "Moreover, TIFA was found to associate with TRAF6 constitutively, whereas its association with IRAK-1 was seen only after hypoxia-reoxygenation. "
06/07/2013 - "Cezanne regulates inflammatory responses to hypoxia in endothelial cells by targeting TRAF6 for deubiquitination."
01/01/2013 - "Taken together, we conclude that Notch signaling is involved in regulating microglia activation after hypoxia partly through the cross talk between TLR4/MyD88/TRAF6/NF-κB pathways. "
01/01/2014 - "We conclude that miR-146a ameliorates liver ischemia/reperfusion injury in vivo and hypoxia/reoxygenation injury in vitro by directly suppressing IRAK1 and TRAF6. "
04/01/2012 - "In addition, our study provides the first evidence of the involvement of endoplasmic reticulum stress and unfolding protein response pathways in starvation-induced muscle atrophy and its regulation through TRAF6. "
04/01/2012 - "Ablation of TRAF6 also improved the phosphorylation of Akt and FoxO3a and inhibited the activation of 5' AMP-activated protein kinase in skeletal muscle in response to starvation. "
04/01/2012 - "Finally, our results also identify lysine 63-linked autoubiquitination of TRAF6 as a process essential for its regulatory role in starvation-induced muscle atrophy."
04/01/2012 - "The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanisms."
05/01/2012 - "Muscle-specific ablation of TRAF6 inhibits the induction of atrophy program in response to starvation, denervation, or cancer cachexia. "
04/01/2015 - "The aim of the present study was to investigate whether TRAF6 is involved in the progression of RA in mouse collagen‑induced arthritis (CIA) and human RA FLSs in vitro. "
04/01/2015 - "Inhibition of TRAF6 using mouse specific siTRAF6 reduced the severity of arthritis and joint inflammation. "
01/01/2014 - "After IFN-β administration, the arthritis scores were decreased; synovial inflammation, cartilage, and bone destruction were clearly attenuated; and the expression of c-Fos and NFATc1 were reduced, while RANKL and TRAF6 expression was unchanged. "
|1.||Interleukin-6 (Interleukin 6)
|2.||AMP-Activated Protein Kinases
|3.||Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
|4.||TNF Receptor-Associated Factor 6 (TRAF6)
|5.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|6.||NF-kappa B (NF-kB)
|8.||Messenger RNA (mRNA)
|10.||Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)
|2.||Drug Therapy (Chemotherapy)
|5.||Heterologous Transplantation (Xenotransplantation)