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Tumor Necrosis Factor Receptor-Associated Peptides and Proteins

Intracellular signaling peptides and proteins that bind directly or indirectly to the cytoplasmic portion of TUMOR NECROSIS FACTOR RECEPTORS.
Also Known As:
TRAF Proteins; TRAF and TNF Receptor-Associated Protein; TRAF and TNF Receptor-Associated Proteins; TRAF-Interacting Protein; TRAF-Interacting Proteins; TRIP Protein, TNF; TTRAP Proteins; Receptor-Associated Factors, TNF; TNF Receptor Associated Factors; TNF TRIP Protein; TRAF Interacting Protein; TRAF Interacting Proteins; TRAF and TNF Receptor Associated Protein; TRAF and TNF Receptor Associated Proteins; Tumor Necrosis Factor Receptor Associated Factors; Tumor Necrosis Factor Receptor Associated Peptides and Proteins; TNF Receptor-Associated Factors; Tumor Necrosis Factor Receptor-Associated Factors
Networked: 23 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Inoue, Jun-Ichiro: 2 articles (10/2015 - 09/2009)
2. Matsumura, Takayuki: 2 articles (10/2015 - 09/2009)
3. Lievens, Dirk: 2 articles (02/2014 - 05/2008)
4. Weber, Christian: 2 articles (02/2014 - 05/2008)
5. Lutgens, Esther: 2 articles (02/2014 - 05/2008)
6. Gerdes, Norbert: 2 articles (02/2014 - 05/2007)
7. Beckers, Linda: 2 articles (02/2014 - 05/2008)
8. Karsan, Aly: 1 article (10/2015)
9. Konno, Hiroyasu: 1 article (10/2015)
10. Meetei, Ruhikanta A: 1 article (10/2015)

Related Diseases

1. Atherosclerosis
2. Necrosis
3. Inflammation
4. Infection
5. Lymphoma (Lymphomas)
05/01/2002 - "Furthermore, the same intracellular distribution of TRAF proteins was demonstrated in H-RS cells of lymph nodes of HD, but not in lymphoma cells in lymph nodes of non-Hodgkin's lymphoma. "
10/15/2004 - "The cDNA-oligoarray analysis and reverse transcription-PCR verification indicated common changes in gene expression in methionine-dependent cell lines to include up-regulation/induction of cyclin D1, mitotic arrest deficient (MAD)1, p21, growth arrest and DNA-damage-inducible (GADD)45 alpha, GADD45 gamma, GADD34, breast cancer (BRCA)1, 14-3-3sigma, B-cell CLL/lymphoma (BCL)1, transforming growth factor (TGF)-beta, TGF-beta-induced early response (TIEG), SMAD5, SMAD7, SMAD2, insulin-like growth factor binding protein (IGFBP7), IGF-R2, vascular endothelial growth factor (VEGF), TNF-related apoptosis-inducing ligand (TRAIL), TNF-alpha converting enzyme (TACE), TRAIL receptor (TRAIL-R)2, TNFR-related death receptor (DR)6, TRAF interacting protein (I-TRAF), IL-6, MDA7, IL-1B convertase (ICE)-gamma, delta and epsilon, IRF1, IRF5, IRF7, interferon (IFN)-gamma and receptor components, ISG15, p65-NF-kappaB, JUN-B, positive cofactor (PC)4, C/ERB-beta, inositol triphosphate receptor I, and methionine adenosyltransferase II. On the other hand, cyclins A1, A2, B1 and B2, cell division cycle (CDC)2 and its kinase, CDC25 A and B, budding uninhibited by benzimidazoles (BUB)1 and 3, MAD2, CDC28 protein kinase (CKS)1 and 2, neuroepithelial cell transforming gene (NET)1, activator of S-phase kinase (ASK), CDC14B phosphatase, BCL2, TGF-beta activated kinase (TAK)1, TAB1, c-FOS, DNA topoisomerase II, DNA polymerase alpha, dihydrofolate reductase, thymidine kinase, stathmin, and MAP4 were down-regulated. "

Related Drugs and Biologics

1. NF-kappa B (NF-kB)
2. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3. Proteins (Proteins, Gene)
4. Membrane Proteins (Integral Membrane Proteins)
5. TNF Receptor-Associated Factor 1
6. Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
7. Phosphotransferases (Kinase)
8. Inositol 1,4,5-Trisphosphate Receptors (Inositol Triphosphate Receptor)
9. TNF Receptor-Associated Factor 4
10. TNF-Related Apoptosis-Inducing Ligand