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Type I Tumor Necrosis Factor Receptors

A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.
Also Known As:
Receptors, Tumor Necrosis Factor, Type I; CD 120a Antigen; CD120a Antigen; TNFR p60; TNFR-I; TNFR1; TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A); TNFRSF1A Receptor; Tumor Necrosis Factor Receptor 1A; Tumor Necrosis Factor Receptor Type 1; 120a Antigen, CD; Antigen, CD 120a; Antigen, CD120a; Receptor, TNFRSF1A; Antigens, CD120a; CD120a Antigens; Receptors, Tumor Necrosis Factor, Member 1A; Tumor Necrosis Factor Receptor Superfamily, Member 1A; Tumor Necrosis Factor Receptor Type I
Networked: 627 relevant articles (29 outcomes, 73 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Tsutsumi, Yasuo: 10 articles (02/2015 - 01/2008)
2. Meldrum, Daniel R: 10 articles (09/2010 - 07/2006)
3. Yoshioka, Yasuo: 9 articles (02/2015 - 01/2008)
4. Kamada, Haruhiko: 8 articles (02/2015 - 01/2008)
5. Mukai, Yohei: 8 articles (02/2015 - 01/2008)
6. Abe, Yasuhiro: 8 articles (02/2015 - 01/2008)
7. Tsunoda, Shin-ichi: 8 articles (02/2013 - 01/2008)
8. Nakagawa, Shinsaku: 8 articles (02/2013 - 01/2008)
9. Wang, Meijing: 8 articles (06/2010 - 07/2006)
10. Nomura, Tetsuya: 7 articles (01/2011 - 01/2008)

Related Diseases

1. Infection
2. Inflammation
3. Ischemia
4. Neoplasms (Cancer)
5. Demyelinating Diseases (Demyelinating Disease)

Related Drugs and Biologics

1. Type II Tumor Necrosis Factor Receptors
2. Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
3. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
4. NF-kappa B (NF-kB)
5. Interleukin-1 (Interleukin 1)
6. Small Interfering RNA (siRNA)
7. Turpentine
8. Caspases
9. Protein Kinases (Protein Kinase)
10. Perforin

Related Therapies and Procedures

1. Ligation
2. Moxibustion
3. Transplants (Transplant)
4. Transplantation (Transplant Recipients)
5. Bone Marrow Transplantation (Transplantation, Bone Marrow)