|1.||Gerwick, William H: 3 articles (03/2015 - 04/2005)|
|2.||Teicher, B A: 3 articles (09/2001 - 01/2000)|
|3.||Shih, C: 3 articles (09/2001 - 01/2000)|
|4.||Amsrud, T: 2 articles (07/2000 - 01/2000)|
|5.||Forler, P: 2 articles (07/2000 - 01/2000)|
|6.||Menon, K: 2 articles (07/2000 - 01/2000)|
|7.||Phares, V: 2 articles (07/2000 - 01/2000)|
|8.||Vining, Oliver B: 1 article (03/2015)|
|9.||Serrill, Jeffrey D: 1 article (03/2015)|
|10.||Li, Dong: 1 article (03/2015)|
|1.||Cardiovascular Diseases (Cardiovascular Disease)
03/01/2015 - "In particular, the potent effects of cyclic depsipeptides on tumor cells have led to a number of clinical trials evaluating their potential as chemotherapeutic agents. "
01/01/2009 - "Cyclodepsipeptides, which are currently being evaluated in clinical trials, are used in refractory cancer therapy, usually in combination with other cytotoxic drugs. "
02/01/2002 - "Four depsipeptides have entered clinical trials for cancer treatment. "
05/27/2011 - "A family of cancer cell cytotoxic cyclodepsipeptides, veraguamides A-C (1-3) and H-L (4-8), were isolated from a collection of cf. "
03/23/2007 - "Destruxins are a class of insecticidal, anti-viral, and phytotoxic cyclic depsipeptides that are also studied for their toxicity to cancer cells. "
|3.||Hepatocellular Carcinoma (Hepatoma)
12/01/2013 - "Two novel hepatocellular carcinoma cycle inhibitory cyclodepsipeptides from a hydrothermal vent crab-associated fungus Aspergillus clavatus C2WU."
12/04/1996 - "Study of structure-activity correlation in destruxins, a class of cyclodepsipeptides possessing suppressive effect on the generation of hepatitis B virus surface antigen in human hepatoma cells."
06/24/2010 - "Similar to the parent system 4a, the series of largazole depsipeptides 4b-d, but not 2,4'-bithiazole 5a, showed a marked inhibition of recombinant HDAC1 and selectivity over HDAC4, as well as strong pro-apoptotic effects on the NB4 leukemia cell line, but they failed to induce differentiation to mature granulocytes. "
03/01/2001 - "An excellent anti-leukemia activity has been found in a group of actinomycin D analogues derivatized at the 2,2'- or 5,5'-position of the depsipeptides. "
02/08/1999 - "Analogs of the antitumor agents cryptophycins 1 and 8 with dialkyl substitution at C-6 (fragment C) were synthesized and evaluated for in vitro cytotoxicity against human leukemia cells (CCRF-CEM). "
05/22/1981 - "The active compounds isolated from the tunicate, didemnins A, B, and C, are depsipeptides, and didemnin B (a derivative of didemnin A) is the component active at the lowest concentration in inhibiting viral replication in vitro and P388 leukemia in vivo."
01/01/1983 - "The most interesting compounds identified thus far are the didemnins, depsipeptides from a Caribbean Trididemnum species, which are potent inhibitors of L1210 leukemia cells in vitro and are also active in vivo against P388 leukemia and B16 melanoma. "
|1.||Antifibrinolytic Agents (Antifibrinolytics)
|4.||Surface Antigens (Surface Antigen)
|2.||Heterologous Transplantation (Xenotransplantation)