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Defibrillators (Defibrillator)

Cardiac electrical stimulators that apply brief high-voltage electroshocks to the HEART. These stimulators are used to restore normal rhythm and contractile function in hearts of patients who are experiencing VENTRICULAR FIBRILLATION or ventricular tachycardia (TACHYCARDIA, VENTRICULAR) that is not accompanied by a palpable PULSE. Some defibrillators may also be used to correct certain noncritical dysrhythmias (called synchronized defibrillation or CARDIOVERSION), using relatively low-level discharges synchronized to the patient's ECG waveform. (UMDNS, 2003)
Also Known As:
Defibrillator; Automated External Defibrillator; Automated External Defibrillators; Defibrillators, External; Electric Shock Cardiac Stimulators; Stimulators, Electrical, Cardiac, Shock; Defibrillator, Automated External; Defibrillator, External; Defibrillators, Automated External; External Defibrillator; External Defibrillator, Automated; External Defibrillators; External Defibrillators, Automated
Networked: 5029 relevant articles (264 outcomes, 643 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1. Zareba, Wojciech: 122 articles (01/2021 - 03/2002)
2. Moss, Arthur J: 122 articles (01/2019 - 03/2002)
3. McNitt, Scott: 113 articles (01/2021 - 10/2004)
4. Kutyifa, Valentina: 82 articles (01/2021 - 04/2013)
5. Goldenberg, Ilan: 77 articles (01/2021 - 10/2005)
6. Boriani, Giuseppe: 47 articles (01/2022 - 01/2002)
7. Polonsky, Bronislava: 38 articles (01/2021 - 04/2009)
8. Saba, Samir: 35 articles (01/2020 - 01/2004)
9. Barsheshet, Alon: 35 articles (03/2019 - 10/2010)
10. Maron, Barry J: 31 articles (01/2022 - 01/2003)

Related Diseases

1. Ventricular Tachycardia
2. Heart Arrest (Cardiac Arrest)
3. Heart Failure
06/01/2010 - "The most recent MADIT-CRT trial showed that a cardiac resynchronization therapy device with defibrillator (CRT-D) was effective in reducing the risk of heart failure or death, whichever came first, in cardiac patients who were asymptomatic or minimally symptomatic (New York Heart Association class I or II) with reduced ejection fraction < or =0.30 and wide QRS complex > or =130 ms when compared with an implantable cardiac defibrillator (ICD) device. "
05/01/2005 - "Consequently, ECP applied at low pressures and average D/S ratios of 0.7:1 under the new graduated pressure regimen is safe and effective in the treatment of CHF and produces a significant reduction in mortality, compared with the 8.5% annualized mortality of the Multicenter Automatic Defibrillator Implantation Trial II (MADIT II) (N=1232) of NYHA class II-III CHF and the 12.2% annual mortality of the Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure (COMPANION) study (N=595) of NYHA class III-IV CHF. "
09/01/2004 - "Newer data suggest a significant reduction in overall mortality and heart failure hospitalization, particularly when CRT is combined with automatic defibrillator backup. "
08/01/2000 - "In patients surviving malignant ventricular arrhythmias, defibrillator implantation is beneficial in elderly patients with heart failure. "
01/01/2007 - "Early studies demonstrated improved functional capacity and evidence of reverse remodeling; more recently, CRT has been associated with a survival benefit in advanced heart failure both with and without a defibrillator. "
4. Cardiac Sudden Death (Sudden Cardiac Arrest)
5. Sudden Death

Related Drugs and Biologics

1. Anti-Arrhythmia Agents
2. Amiodarone (Amiodarona)
3. Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)
4. Gadolinium
5. Urea (Carbamide)
6. Nitrogen
7. Anti-Bacterial Agents (Antibiotics)
8. Amsacrine (AMSA)
9. Adrenergic beta-Antagonists (beta-Adrenergic Blocking Agents)
10. Anthracyclines

Related Therapies and Procedures

1. Therapeutics
2. Cardiac Resynchronization Therapy
3. Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
4. Cardiopulmonary Resuscitation (CPR)
5. Resuscitation