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Massive Hepatic Necrosis

Extensive and rapid death of parenchymal cells in the LIVER, often due to exposure to toxic materials or drug-induced injury. It is characterized by a soft, flabby, yellow-brown wrinkled, and shrunken liver. It was called "acute yellow atrophy".
Also Known As:
Acute Yellow Atrophy; Acute Yellow Atrophy of Liver; Acute Yellow Atrophies; Drug induced Hepatic Necrosis; Drug-induced Hepatic Necroses; Fulminant Hepatitides; Hepatic Necrosis, Drug-induced; Hepatic Necrosis, Massive; Hepatic Necrosis, Submassive; Necrosis, Drug-induced Hepatic; Necrosis, Submassive Hepatic; Submassive Hepatic Necroses; Yellow Atrophy, Acute; Drug-induced Hepatic Necrosis; Fulminant Hepatitis; Hepatitis, Fulminant; Submassive Hepatic Necrosis
Networked: 1539 relevant articles (54 outcomes, 102 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hepatitis
2. Massive Hepatic Necrosis
3. Acute Liver Failure (Fulminant Hepatic Failure)
4. Infections
5. Inflammation (Inflammations)

Experts

1. Ning, Qin: 16 articles (01/2022 - 05/2003)
2. Yokosuka, Osamu: 12 articles (02/2019 - 02/2003)
3. Suzuki, Kazuyuki: 12 articles (08/2009 - 11/2001)
4. Xi, Dong: 10 articles (01/2022 - 11/2005)
5. Fujiwara, Keiichi: 10 articles (02/2019 - 02/2003)
6. Okamoto, Hiroaki: 10 articles (01/2018 - 07/2005)
7. Tian, Zhigang: 9 articles (05/2014 - 11/2005)
8. Zhang, Li: 8 articles (08/2021 - 07/2014)
9. Mochida, Satoshi: 8 articles (04/2021 - 08/2004)
10. Luo, Xiaoping: 8 articles (01/2019 - 06/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Massive Hepatic Necrosis:
1. Lamivudine (Epivir)FDA Link
2. Hepatitis B Surface Antigens (HBsAg)FDA Link
3. GalactosamineIBA
4. LipopolysaccharidesIBA
5. Concanavalin AIBA
6. Proteins (Proteins, Gene)FDA Link
7. CytokinesIBA
8. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
9. Transaminases (Aminotransferases)IBA
10. Acetaminophen (Paracetamol)FDA LinkGeneric

Therapies and Procedures

1. Liver Transplantation
2. Therapeutics
3. Transplantation
4. Plasma Exchange
5. Bone Marrow Transplantation (Transplantation, Bone Marrow)