|1.||Cochet, Claude: 12 articles (09/2015 - 03/2002)|
|2.||Pinna, Lorenzo A: 11 articles (01/2013 - 03/2003)|
|3.||Ahmed, Khalil: 10 articles (01/2015 - 01/2002)|
|4.||Issinger, Olaf-Georg: 8 articles (08/2015 - 10/2007)|
|5.||Guerra, Barbara: 8 articles (08/2015 - 01/2008)|
|6.||Jose, Joachim: 8 articles (01/2015 - 04/2010)|
|7.||Bae, Young-Seuk: 8 articles (08/2014 - 02/2006)|
|8.||Litchfield, David W: 8 articles (07/2013 - 05/2002)|
|9.||Ruzzene, Maria: 7 articles (01/2013 - 09/2004)|
|10.||Prudent, Renaud: 7 articles (12/2011 - 07/2008)|
02/23/2001 - "A potential role of nuclear matrix-associated protein kinase CK2 in protection against drug-induced apoptosis in cancer cells."
01/01/2014 - "Here, we report that CX-4945, a previously well-characterized inhibitor of casein kinase 2 (CK2) and a molecule currently in clinical trials (Phase II) for cancer treatment, regulates splicing in mammalian cells in a CK2-independent manner. "
08/01/2012 - "Inhibitors of casein kinase 2 (CK2), a regulator of cell proliferation and mediator of the DNA damage response, are being evaluated in clinical trials for the treatment of cancers. "
10/04/2011 - "Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer."
03/15/2005 - "In this study, we analyze the mechanisms of apoptosis associated with 6-TG treatment and casein kinase 2 (CK2 or CKII) in human tumor cells. "
10/08/2015 - "We show that Ikaros function is impaired by the pro-oncogenic casein kinase II (CK2), and that CK2 is overexpressed in leukemia. "
01/01/2010 - "CALLA and protein kinase CK2 revisited: targetable molecules for treating patients with leukemia?"
10/08/2015 - "Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia."
08/01/2008 - "This study was to observe the effects of mitoxantrone on the activity of recombinant holoenzyme of human protein kinase CK2 and proliferation in human leukemia cell line HL-60. "
08/01/2008 - "Protein kinase CK2, a highly conserved protein serine/threonine kinase that is ubiquitously distributed in eukaryotes, has a close relationship with human leukemia. "
01/01/2013 - "Protein kinase CK2 is a critical regulator of epithelial homeostasis in chronic intestinal inflammation."
01/01/2012 - "Protein kinase CK2 is a potential drug target for many diseases including cancer and inflammation disorders. "
10/01/2015 - "Dimethyl fumarate ameliorated inflammation, reduced blood-brain barrier permeability, and improved neurological outcomes by casein kinase 2 and Nrf2 signaling pathways after experimental ICH in mice."
12/01/2013 - "Emodin is a pleiotropic molecule capable of interacting with several major molecular targets including NF-κB, casein kinase II, HER2/neu, HIF-1α, AKT/mTOR, STAT3, CXCR4, topoisomerase II, p53, p21, and androgen receptors which are involved in inflammation and cancer. "
09/06/2002 - "In this study, we have evaluated the role of casein kinase 2 (CK2) during Mayaro virus infection cycle. "
05/01/2015 - "Casein kinase II controls TBK1/IRF3 activation in IFN response against viral infection."
07/01/2006 - "Molecular cloning of a Trypanosoma cruzi cell surface casein kinase II substrate, Tc-1, involved in cellular infection."
09/06/2002 - "Mayaro virus infection cycle relies on casein kinase 2 activity."
11/02/2006 - "Due to the emerging role of protein kinase CK2 as a molecule that participates not only in the development of some cancers but also in viral infections and inflammatory failures, small organic inhibitors of CK2, besides application in scientific research, may have therapeutic significance. "
|3.||Casein Kinase II (Casein Kinase 2)
|4.||NF-kappa B (NF-kB)
|5.||Protein Kinases (Protein Kinase)
|7.||Protein Kinase C
|8.||Staphylococcal Protein A (A, Protein)
|9.||Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)
|10.||DNA (Deoxyribonucleic Acid)
|1.||Heterologous Transplantation (Xenotransplantation)