|1.||Zhu, Li: 6 articles (02/2011 - 11/2004)|
|2.||Du, Fang: 3 articles (02/2011 - 08/2007)|
|3.||Ke, Ya: 2 articles (02/2011 - 01/2008)|
|4.||Yung, Wing Ho: 2 articles (02/2011 - 01/2008)|
|5.||Li, Zhu: 2 articles (09/2009 - 02/2008)|
|6.||Ya, Ke: 2 articles (09/2009 - 02/2008)|
|7.||Ming, Qian Zhong: 2 articles (09/2009 - 02/2008)|
|8.||Wu, Xiao-Mei: 2 articles (08/2007 - 11/2004)|
|9.||Wang, Zhen-zhong: 1 article (12/2014)|
|10.||Geng, Ting: 1 article (12/2014)|
02/01/2011 - "These findings imply that the timing of treatment with hypothermia and/or ginkgolides is one of the key factors to determine their protective effects on the cells against the I/R injury."
09/01/2009 - "We demonstrated that ginkgolides, but not hypothermia, have a significantly time- and concentration-dependent protective role in ischemic astrocytes. "
09/01/2009 - "The neuroprotective roles of both hypothermia and ginkgolides have been well confirmed. "
09/01/2009 - "Hypothermia attenuates protective effects of ginkgolides on astrocytes from ischemia/reperfusion injury."
09/01/2009 - "Western blot analysis demonstrated that hypothermia (32 or 28 degrees C for 24h) has no effect on the expression of Hypoxia-inducible factor-1 alpha (HIF-1 alpha) protein, suggesting that HIF-1 alpha is not associated with the adverse effect of hypothermia on ginkgolides. "
12/02/2014 - "The extracts of Ginkgo biloba leaves are effective in treating cerebral infarction, of which ginkgolides have been demonstrated to be the active ingredients. "
05/01/2006 - "The middle cerebral artery occlusion (MACO) model was induced by the FeCl3-occluding method to explore the protective effects of ginkgolides injection on the score of neurological deficits, the rate of cerebral infarction and the histomorphology of cerbral ischemia in rats. "
11/01/2007 - "To study the effects of ginkgolides (Gin) on the expression of hypoxia-inducible factor-1alpha (H1F-1alpha) in primary cultured cortical neurons treated with CoCl2 and the relationship with ERK signal pathway. "
11/01/2004 - "To study the effects of ginkgolides (Gin) on the expression of hypoxia inducible factor-1 (HIF-1alpha) in hypoxic/ischemic neurons. "
02/01/2008 - "Our data demonstrated that ginkgolides have a significant protective role against hypoxia-induced injury in the PC12 cells. "
01/01/2008 - "The similar tendency in the changes of protein expression, cell viabilities and responses to MAPK or PI3K inhibitors of the cells treated with ginkgolides and hypoxia suggests that ginkgolides and hypoxic preconditioning might operate by similar mechanisms. "
01/01/2008 - "To find a safer preconditioning stimulus that is both practical and effective, we investigated whether ginkgolides are capable of preconditioning as hypoxia to protect C6 cells against ischemic injury. "
02/01/2014 - "We have previously reported that ginkgolides containing ginkgolides A and B (GKAB) reduce infarct size in a rat model of focal ischemia. "
09/01/2009 - "Cells were incubated with 18.75, 37.5 or 75 microg/ml of ginkgolides at 37, 32 or 28 degrees C for 24, 48 or 72 h before exposure to ischemia (24h) and then reperfusion (24h). "
09/11/2007 - "The pretreatment of Ginkgolides could induce tolerance against ischemia in PC12 cells. "
09/11/2007 - "Pretreatment of Ginkgolides for 24 hours could largely rescue the morphology of PC12 cells to the damage of subsequent exposure to 9 hours ischemia insult, many cellular bodies were intact and many neurites and network of PC12 cells were still exist. "
09/11/2007 - "PC12 cells was randomly divided into four groups: 9 hours ischemia group, 1.5 hours ischemic preconditioning + 9 hours ischemia group, Ginkgolides preconditioning + 9 hours ischemia group and control group. "
|5.||Alzheimer Disease (Alzheimer's Disease)
01/01/1998 - "An exception is Ginkgo biloba in which the ginkgolides have antioxidant, neuroprotective, and cholinergic activities relevant to Alzheimer's disease mechanisms. "
07/01/2004 - "As Ginkgo has been shown to improve age-related memory de fi cits and beta-amyloid-related peptides have been suggested to play a signi fi cant role in memory degeneration in Alzheimer's disease, the present study was carried out to examine the effect of two major ginkgolides, A and B, on beta-amyloid peptide-modulated acetylcholine (ACh) release from hippocampal brain slices. "
|2.||Acetylcholine (Acetylcholine Chloride)
|3.||Plant Preparations (Preparation, Plant)
|6.||Amyloid (Amyloid Fibrils)
|9.||Complement System Proteins (Complement)
|10.||Ginkgo biloba extract 761 (Rokan)