|1.||Chiba, Naoko: 5 articles (06/2011 - 05/2004)|
|2.||Ubukata, Kimiko: 5 articles (06/2011 - 05/2004)|
|3.||Sunakawa, Keisuke: 3 articles (06/2011 - 05/2004)|
|4.||Suzumoto, Masaki: 3 articles (03/2006 - 01/2002)|
|5.||Hotomi, Muneki: 3 articles (03/2006 - 01/2002)|
|6.||Yamanaka, Noboru: 3 articles (03/2006 - 01/2002)|
|7.||Shimada, Jun: 3 articles (03/2006 - 01/2002)|
|8.||Mobashery, Shahriar: 2 articles (07/2014 - 04/2004)|
|9.||Rajagopalan, M: 2 articles (12/2013 - 07/2011)|
|10.||Madiraju, M: 2 articles (12/2013 - 07/2011)|
09/01/1979 - "This study was undertaken to determine if the categorization of Neisseria gonorrhoeae strains into disseminated gonococcal infection (DGI) and non-DGI types was also paralleled by some common characteristic in their penicillin-binding proteins (PBPs). "
10/12/1979 - "After infection with this hybrid phage, penicillin-binding protein 3 was overproduced and incorporated into the E. "
11/11/2015 - "Here we show that the protein conferring β-lactam antibiotic resistance, penicillin-binding protein 2A (encoded by the mecA gene), directly contributes to pathogenicity during MRSA infection. "
07/16/2014 - "Ceftaroline, a recently approved β-lactam antibiotic for treatment of infections by methicillin-resistant Staphylococcus aureus (MRSA), is able to inhibit penicillin-binding protein 2a (PBP2a) by triggering an allosteric conformational change that leads to the opening of the active site. "
01/01/2013 - "Although β-lactam antimicrobials have thus far been a mainstay of the therapeutic armamentarium for treatment of severe infections, their preeminent position has been challenged by an onslaught of resistance mechanisms in major nosocomial and community-acquired pathogens, including modification of penicillin-binding proteins, production of β-lactamases, overexpression of efflux pumps, and loss of porins. "
06/01/2011 - "We examined associations of serotypes with multilocus sequence typing (MLST) data for 7 housekeeping genes and the genotype concerning penicillin resistance based on penicillin-binding protein (PBP) alterations in Streptococcus pneumoniae isolates from children with meningitis. "
05/01/2004 - "Antibiotic susceptibility in relation to penicillin-binding protein genes and serotype distribution of Streptococcus pneumoniae strains responsible for meningitis in Japan, 1999 to 2002."
11/01/1990 - "Cefuroxime treatment failure of nontypable Haemophilus influenzae meningitis associated with alteration of penicillin-binding proteins."
06/01/1995 - "A polymerase chain reaction (PCR) assay based on the penicillin-binding protein gene PBP2B identified the presence of DNA specific for Streptococcus pneumoniae in the serum and CSF of a patient with culture-proven bacteremia and meningitis. "
04/01/2007 - "Strains with alterations in penicillin binding proteins, particularly PBP3 (beta-lactamase negative ampicillin resistant and beta-lactamase positive amoxicillin-clavulanate resistant), are increasing in prevalence, particularly in Japan, with increasing resistance to ampicillin, amoxicillin, amoxicillin-clavulanate, and many cephalosporins, limiting the efficacy of expanded-spectrum cephalosporins against meningitis and of many oral cephalosporins against other diseases. "
12/01/1999 - "The latter included a gradual reduction in the proportion of highly cross-linked muropeptide species in peptidoglycan, down-regulation of the production of penicillin-binding protein 2A (PBP2A) and PBP4, and hypersensitivity to beta-lactam antibiotics each with a relatively selective affinity for the various staphylococcal PBPs; the PBP2-specific inhibitor ceftizoxime was particularly effective."
03/01/2006 - "influenzae with mutations in the ftsI gene encoding penicillin-binding protein 3 (PBP3) among children with otitis media. "
03/01/2006 - "A high prevalence of penicillin-binding protein gene-mutated (PGM) strains of Haemophilus influenzae should be taken into account when treating otitis media in children. "
12/01/2003 - "We studied, by pulsed-field gel electrophoresis, multilocus sequence typing and penicillin-binding protein 2b amplicon-restriction profiles, pneumococcal isolates recovered from children with acute otitis media during 1 January-31 December 1999 and 2001. "
01/01/2002 - "A polymerase chain reaction (PCR)-based genotyping of the penicillin-binding protein (PBP) genes pbp1a, pbp2x and pbp2b was used to characterize Streptococcus pneumoniae isolated from the nasopharynx of children with acute otitis media (AOM). "
01/01/2002 - "Nasopharyngeal carriage of drug-resistant Streptococcus pneumoniae in children with acute otitis media evaluated by polymerase chain reaction-based genotyping of penicillin-binding proteins."
07/01/2014 - "PonA2 is one of the two class A penicillin binding proteins of Mycobacterium tuberculosis, the etiologic agent of tuberculosis. "
07/01/2011 - "tuberculosis CrgA with FtsZ, FtsQ, and the class B penicillin-binding proteins, FtsI (PBPB) and PBPA. "
09/01/2000 - "tuberculosis as a penicillin-binding protein, in biotin biosynthesis and as a polyketide synthase. "
06/01/1998 - "tuberculosis genome, one of which encoded a protein with 35% identity to a low-affinity penicillin-binding protein (PBP) from Streptomyces clavuligerus. "
12/01/2013 - "tuberculosis led to increased sensitivity to cefsulodin, a penicillin-binding protein (PBP) 1A/1B targeting beta (β) -lactam, but was unaffected by other β-lactams and vancomycin. "
|3.||Anti-Bacterial Agents (Antibiotics)
|6.||Cephalosporins (Cephalosporin Antibiotics)
|8.||Clavulanic Acid (Potassium Clavulanate)
|1.||Drug Therapy (Chemotherapy)