An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.
Also Known As:
Syndrome, Laron; Growth Hormone Receptor Defect; Growth Hormone Receptor Deficiency; Laron Dwarfism; Laron Type Dwarfism I; Pituitary Dwarfism II; Primary GH Resistance; Primary Growth Hormone Resistance; Severe GH Insensitivity; Dwarfism II, Pituitary; Dwarfism IIs, Pituitary; Dwarfism, Laron; GH Resistance, Primary; Pituitary Dwarfism IIs; Growth Hormone Insensitivity Syndrome